{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:10:06Z","timestamp":1789679406238,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T00:00:00Z","timestamp":1757289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To describe clinical features, risk factors and outcomes of out\u2010of\u2010the\u2010bag (OTB) intraocular lens (IOL) dislocation in dead bag syndrome (DBS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective review of a single\u2010surgeon series of eyes with IOLs that developed OTB IOL dislocation, managed at Singapore National Eye Centre (January 2014\u2013December 2021), with a minimum of 6\u2009months of follow\u2010up. Eyes with OTB IOL dislocation following secondary IOL implantation and intraoperative capsule complications were excluded. Patient demographics, ocular history, clinical findings, ocular trauma\/eye rubbing, surgical procedures and postoperative outcomes were obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty eyes (40 unilateral, 5 bilateral) of 45 patients were included. Patients were predominantly male (82.2%), presenting at 61.9\u2009\u00b1\u200914.1\u2009years old, 11.2\u2009\u00b1\u20096.0\u2009years after cataract surgery. Eye rubbing was the only form of ocular trauma (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200934; 68.0%). Compared to non\u2010eye rubbers, eye rubbers were significantly more likely to have elevated intraocular pressure (IOP) (32.4% vs. 6.2%; OR 10.9, 95% confidence interval [CI] 1.12\u2013107;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040), larger posterior capsule defects (median 60% vs. 50%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.029), vitreous in the anterior chamber (38.2% vs. 6.2%; OR 10.3, 95% CI 1.05\u2013101;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.045) and lower endothelial cell counts than the non\u2010affected eye (\u2212145\u2009\u00b1\u2009507 vs. 315\u2009\u00b1\u2009639 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      ;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.026). The most common complications after IOL exchange were elevated IOP (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911; 22.0%) including glaucoma (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20098; 16.0%) and recurrent IOL subluxation (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097; 14.0%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Eye rubbing appears to play an important role in the development of OTB IOL dislocations in DBS and is associated with more severe clinical manifestations. Treating the underlying cause and counselling patients to avoid or minimise eye rubbing may reduce this complication.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ceo.14606","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T05:52:53Z","timestamp":1757397173000},"page":"1115-1124","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Out\u2010Of\u2010The\u2010Bag Intraocular Lens Dislocation in Dead Bag Syndrome and Its Association With Eye Rubbing"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6308-5721","authenticated-orcid":false,"given":"Soon\u2010Phaik","family":"Chee","sequence":"first","affiliation":[{"name":"Singapore National Eye Centre  Singapore Singapore"},{"name":"Department of Ophthalmology, Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"},{"name":"Cataract Research Team Singapore Eye Research Institute  Singapore Singapore"},{"name":"Department of Ophthalmology &amp; Visual Sciences Academic Clinical Program Duke\u2010NUS Medical School  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7313-2202","authenticated-orcid":false,"given":"Nicole Shu\u2010Wen","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"},{"name":"Department of Ophthalmology National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia Xu","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery National Neuroscience Institute  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.09.017"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.jcrs.0000000000000742"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e3282ced08e"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2009.02.025"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.03.036"},{"issue":"3","key":"e_1_2_8_7_1","first-page":"71","article-title":"The Closed Chamber Slipping Suture Technique for Iris Repair","volume":"26","author":"Siepser S. 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