{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:22:49Z","timestamp":1789086169846,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To evaluate the clinical outcomes of femtosecond laser\u2010created corneal allogenic intrastromal ring segments (femto\u2010CAIRS) in keratoconic eyes using a newly described nomogram.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective case series recruited 85 eyes from 75 patients. Corrected and uncorrected visual acuity (CDVA\/UDVA), refractive error, corneal topography, and higher\u2010order aberrations were measured prior to surgery and \u2265\u20093\u2009months postoperatively. All CAIRS were created using a femtosecond laser and the Brisbane nomogram was used to determine segment width, thickness, arc length, implantation axis and channel depth based on individual corneal topography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean follow\u2010up time was 7.5\u2009\u00b1\u20095.0\u2009months; 18 eyes had prior cross\u2010linking (CXL), 30 underwent simultaneous CXL, and 37 had no CXL. Postoperatively, UDVA improved by 0.4 logMAR (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and CDVA by 0.2 logMAR (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). There was an improvement of 5 or more lines in 31 eyes (43.7%), 8 eyes (11.3%) had no change in UDVA, 1 eye lost 1 line, and 1 eye lost 2 lines. There was a significant reduction in the mean spherical equivalent, refractive astigmatism, flat K, steep K, mean K, and KMax, and an improvement in total higher order aberrations and vertical coma (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Reduction in KMax was greater in eyes that underwent simultaneous CXL compared to those without CXL (\u22124.28D vs. \u22120.70D;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018). No significant complications occurred.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Femto\u2010CAIRS guided by the Brisbane nomogram provides a tailored treatment approach that improved visual acuity and regularisation of the central cornea. Further studies are required to validate our nomogram and clarify the effect of cross\u2010linking on CAIRS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ceo.70104","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:35:54Z","timestamp":1773408954000},"page":"664-677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Femtosecond Laser Created Corneal Allogenic Intrastromal Ring Segments for Keratoconus"],"prefix":"10.1111","volume":"54","author":[{"given":"David J.","family":"Gunn","sequence":"first","affiliation":[{"name":"Queensland Eye Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5124-6228","authenticated-orcid":false,"given":"Rebecca A.","family":"Cox","sequence":"additional","affiliation":[{"name":"Queensland Eye Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Cronin","sequence":"additional","affiliation":[{"name":"Queensland Eye Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886\u20103350(00)00451\u2010X"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081\u2010597X\u201019890501\u201013"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1755\u20103768.2009.01605.X"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S166538"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.SURVOPHTHAL.2023.09.005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X\u201020191010\u201002"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200208000-00006"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886\u20103350(02)02055\u20102"},{"key":"e_1_2_9_10_1","first-page":"212","article-title":"New Surgical Approaches to the Management of KERATOCONUS and Post\u2010Lasik Ectasia","volume":"104","author":"Tan B. 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