{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T20:14:39Z","timestamp":1783455279181,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:00:00Z","timestamp":1776038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:00:00Z","timestamp":1776038400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To synthesise available evidence on the prevalence, treatment strategies, and outcomes of corneal disease affecting Aboriginal and Torres Strait Islander peoples in Australia, and to identify gaps in the existing literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review with narrative synthesis was conducted in accordance with PRISMA 2020 guidelines. PubMed, Embase, Scopus, and the Cochrane Library were searched from January 2010 to February 2025. Eligible studies reported epidemiology and\/or treatment outcomes of corneal disease in Indigenous Australians. Due to heterogeneity, meta\u2010analysis was not performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010one studies met inclusion criteria. Active trachoma prevalence declined over the past decade from approximately 14%\u201315% (1\u20135) to 3%\u20134% (6\u20138), with most jurisdictions reporting prevalence below endemic thresholds by 2022, although pockets of higher prevalence persisted in some remote communities (8). Trachomatous trichiasis was higher among Indigenous Australian adults compared with non\u2010Indigenous Australian adults (~0.4%\u20130.5% vs. ~0.03%\u20130.05%) (5, 8, 9). Evidence for non\u2010trachomatous corneal disease was limited to clinic and hospital\u2010based cohort studies. These data suggested that pterygium was common among Indigenous Australians, although lacked population\u2010level prevalence estimates. Hospital\u2010based keratitis cohorts demonstrated worse visual outcomes among Indigenous patients, with distinct risk factor profiles characterised by lower contact lens use and higher rates of trauma and delayed presentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While available data suggest progress in some corneal conditions among Indigenous Australians, major evidence gaps limit reliable estimates for several pathologies. Priorities include strengthening Indigenous\u2010specific population data and developing prevention and treatment approaches tailored to environmental exposures and access barriers in remote communities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ceo.70118","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T17:24:36Z","timestamp":1776101076000},"page":"653-663","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence, Treatment, and Outcomes of Corneal Disease in Aboriginal and Torres Strait Islander Peoples in Australia: A Systematic Review"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5269-5957","authenticated-orcid":false,"given":"Angus","family":"van der Nagel","sequence":"first","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health The University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cool","sequence":"additional","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health The University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himal","family":"Kandel","sequence":"additional","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health The University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Watson","sequence":"additional","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health The University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(17)30393-5"},{"issue":"11","key":"e_1_2_9_3_1","first-page":"844","article-title":"Global Data on Visual Impairment in the Year 2002","volume":"82","author":"Resnikoff S.","year":"2004","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_9_4_1","unstructured":"Organisation WH \u201cGlobal Elimination of Blinding Trachoma \u201d2013 https:\/\/www.who.int\/publications\/i\/item\/wha51.11."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.06.001"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02532.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.13081"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.12643"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed9060127"},{"issue":"3","key":"e_1_2_9_10_1","article-title":"Australian Trachoma Surveillance Annual Report, 2010","volume":"36","author":"Cowling C. 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