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Follow up scan at 16 and 18 weeks of gestation confirmed the severe exomphalos and detected micrognathia and tetralogy of<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>allot. Array comparative genomic hybridization (a\u2010<jats:styled-content style=\"fixed-case\">CGH<\/jats:styled-content>) further demonstrated a 408\u2009kb 15q11.2 microduplication, with the father\u2010to\u2010be as healthy carrier. This is the first case of an association between 15q11.2 micorduplication and fetal sonographic anomalies. Genetic counseling for estimation of recurrent risk of congenital anomalies is discussed.<\/jats:p>","DOI":"10.1111\/cga.12078","type":"journal-article","created":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T00:29:51Z","timestamp":1422577791000},"page":"65-70","source":"Crossref","is-referenced-by-count":5,"title":["408\u2009kb 15q11.2 microduplication by array comparative genomic hybridization in a fetus presenting with exomphalos, micrognathia, tetralogy of<scp>F<\/scp>allot and normal karyotype: A genetic counseling dilemma in paternal carrier status"],"prefix":"10.1111","volume":"55","author":[{"given":"Gabriele","family":"Tonni","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Prenatal Diagnostic Service Guastalla Civil Hospital AUSL Reggio Emilia Guastalla Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Bellotti","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Prenatal Diagnostic Service San Paolo Hospital University of Milan Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella","family":"Palmisano","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Prenatal Diagnostic Service Guastalla Civil Hospital AUSL Reggio Emilia Guastalla Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola","family":"Alesi","sequence":"additional","affiliation":[{"name":"Medical Genetics Department S. 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