{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:36:32Z","timestamp":1761510992990},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,7,26]],"date-time":"2015-07-26T00:00:00Z","timestamp":1437868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Congenital Anomalies"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Undescended testis (cryptorchidism) is a common structural birth defect, i.e. congenital abnormality of the male genital organs and increasing trend in its birth prevalence was reported in some countries. The aim of this study was to analyze the recorded annual birth prevalence of isolated undescended testis (<jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content>) in the population\u2010based large dataset of the <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ungarian Congenital Abnormality Registry for the period between 1962 and 2011, i.e. during the last 50 years. Cases with <jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content> reported after births were evaluated, and their annual rate per 1000 live\u2010births was calculated. The rates of cases with <jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content> were compared with the so\u2010called true rate of <jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content> measured in a previous clinical\u2010epidemiological study based on the personal examination of 10\u2009203 newborn infants. The birth prevalence of cases with recorded <jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ungary was lower than expected based on the true rate of <jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content>. Thus the two waves in the rate of <jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content> were connected with the different completeness of reporting. In conclusion the birth prevalence of cases with <jats:styled-content style=\"fixed-case\">IUT<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ungary did not indicate a real increasing trend during the last 50 years.<\/jats:p>","DOI":"10.1111\/cga.12106","type":"journal-article","created":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T06:29:33Z","timestamp":1423031373000},"page":"145-149","source":"Crossref","is-referenced-by-count":4,"title":["No increases in the rate of undescended testis in <scp>H<\/scp>ungary during the last 50 years: A population\u2010based study"],"prefix":"10.1111","volume":"55","author":[{"given":"Stelios","family":"Mavrogenis","sequence":"first","affiliation":[{"name":"Department of Uro\u2010oncology National Institute of Oncology  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e1ndor","family":"\u00c1cs","sequence":"additional","affiliation":[{"name":"Second Department of Obstetrics and Gynecology School of Medicine Semmelweis University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew E.","family":"Czeizel","sequence":"additional","affiliation":[{"name":"Foundation for the Community Control of Hereditary Diseases  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910590108"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.92.1.44"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15998-9"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.305.6854.609"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)92697-7"},{"key":"e_1_2_5_7_1","first-page":"1462","article-title":"Increasing trends in congenital malformations of male external organs","volume":"1","author":"Czeizel AE","year":"1985","journal-title":"Lancet"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02343229"},{"key":"e_1_2_5_9_1","doi-asserted-by":"crossref","unstructured":"CzeizelAE.1993.Epidemiological studies of congenital abnormalities in Hungary. 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