{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:13:40Z","timestamp":1790676820901,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Congenital Anomalies"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This is the first population\u2010based study in Thailand on the prevalence of congenital limb defects (CLD). Data were obtained from recently established birth defects registries in three southern Thailand provinces during 2009\u20132013. Entries in the birth defects registries included live births, stillbirths after 24\u2009weeks gestational age, and terminations of pregnancy following a prenatal diagnosis of fetal anomaly. The total of 186\u2009393 births recorded included 424 CLD cases, giving an average prevalence of 2.27 per 1000 births (95% CI, 2.05\u20132.49). The most common CLD was talipes equinovarus (44.1%), followed by polydactyly (13.9%) and syndactyly (9.4%). The prevalence significantly increased with maternal age from 1.81 in mothers aged &lt;30\u2009years to 2.75 in mothers 30 to \u2009&lt;\u200935\u2009years, and to 2.94 in mothers \u226535\u2009years (<jats:italic>P\u2009=<\/jats:italic>\u20090.004). Overall 9.4% of the CLDs were syndromic CLD, again with significantly greater percentages in pregnant women aged \u226535\u2009years than the non\u2010syndromic CLD (32.5% vs 17.5% respectively, <jats:italic>P\u2009=<\/jats:italic>\u20090.03). In conclusion, the overall prevalence of CLD in the 3 southern Thailand provinces examined was 2.27 per 1000 births, and syndromic CLD was significantly higher in pregnant women aged \u226535\u2009years than younger pregnant women.<\/jats:p>","DOI":"10.1111\/cga.12154","type":"journal-article","created":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T04:08:42Z","timestamp":1452053322000},"page":"203-208","source":"Crossref","is-referenced-by-count":16,"title":["Prevalence of congenital limb defects: Data from birth defects registries in three provinces in Southern Thailand"],"prefix":"10.1111","volume":"56","author":[{"given":"Somchit","family":"Jaruratanasirikul","sequence":"first","affiliation":[{"name":"Department of Pediatrics Prince of Songkla University  Hat Yai Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boonsin","family":"Tangtrakulwanich","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery and Physical Medicine Prince of Songkla University  Hat Yai Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pornruedee","family":"Rachatawiriyakul","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Prince of Songkla University  Hat Yai Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hutcha","family":"Sriplung","sequence":"additional","affiliation":[{"name":"Epidemiology Unit Faculty of Medicine Prince of Songkla University  Hat Yai Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wannee","family":"Limpitikul","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Medical Education Center Songkhla Hospital  Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pathikan","family":"Dissaneevate","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Medical Education Center Hatyai Hospital  Hatyai Thailand Songkhla"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nattasit","family":"Khunnarakpong","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Medical Education Center Trang Hospital  Trang Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pongsak","family":"Tantichantakarun","sequence":"additional","affiliation":[{"name":"Pediatric Unit Phatthalung Hospital  Phatthalung Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/11.3.239"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970131218"},{"key":"e_1_2_8_4_1","unstructured":"Bureau of Policy and Strategy Office of the Permanent Secretary Ministry of Public Health Thailand.2011.Public health statistics 2011 [internet]. 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