{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:55:18Z","timestamp":1784919318752,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Congenital Anomalies"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Congenital vaginal atresia is a rare congenital reproductive tract abnormality. To assess the clinical manifestations and feasibility of preserving uterus for congenital complete vaginal atresia with cervical aplasia, nineteen cases who underwent surgical treatment in West China Second Hospital of Sichuan University were retrospectively studied. The cervical status, clinical manifestations, the rate of vaginal re\u2010stenosis and pelvic inflammation after surgery were assessed. Additional 101 similar cases searched through digital Pub Med were included to analyze the feasibility of preserving the uterus. Periodic abdominal pain, primary amenorrhea, and pelvic mass were the primary signs and symptoms. According to the magnetic resonance imaging (MRI), all the uterine cavities expanded, and the atresia sites were above the inner urethral orifice. Data of the cases preserving uteri from both our hospital and the literature showed the rate of re\u2010stenosis in patients with external cervical obstruction was 15.9% while it was 40% in the other types of cervical aplasia (<jats:italic>P<\/jats:italic>\u00a0=\u2009.026). The rate of recurrent pelvic inflammation and hysterectomy was 2.3% for cervical external os obstruction and 8% for the other cervical aplasia types(<jats:italic>P<\/jats:italic>\u00a0=\u2009.296). In conclusion, vaginoplasty and cervicovaginal anastomosis could preserve the fertility for complete vaginal atresia with cervical external os obstruction.<\/jats:p>","DOI":"10.1111\/cga.12417","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T09:17:19Z","timestamp":1617873439000},"page":"127-132","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Clinical features of congenital complete vaginal atresia combined with cervical aplasia: A retrospective study of 19 patients and literature review"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7061-6757","authenticated-orcid":false,"given":"Ling","family":"Mei","sequence":"first","affiliation":[{"name":"Gynecologic Department West China Second Hospital of Sichuan University  Chengdu Sichuan China"},{"name":"Center for Translational Medicine Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Center for Translational Medicine Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second Hospital of Sichuan University  Chengdu Sichuan China"},{"name":"Department of Radiology West China Second Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueyue","family":"Chen","sequence":"additional","affiliation":[{"name":"Gynecologic Department West China Second Hospital of Sichuan University  Chengdu Sichuan China"},{"name":"Center for Translational Medicine Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Niu","sequence":"additional","affiliation":[{"name":"Gynecologic Department West China Second Hospital of Sichuan University  Chengdu Sichuan China"},{"name":"Center for Translational Medicine Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)59942-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/det098"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr021"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-012-3121-7"},{"issue":"4","key":"e_1_2_7_6_1","first-page":"217","article-title":"Congenital vaginal atresia: report of 16 cases","volume":"37","author":"Leng J","year":"2002","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/2047-783X-19-10"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcs.1821"},{"issue":"1","key":"e_1_2_7_9_1","first-page":"31","article-title":"et al","volume":"6","author":"Kobayashi 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