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However, the \u2018<jats:styled-content style=\"fixed-case\">Medical Genome<\/jats:styled-content>\u2019 includes all the functional genomic elements for which genotypic variability is a source of pathogenic phenotypes. This short review focuses on examples of pathogenic variants in non\u2010protein\u2010coding gene regions. It is likely that the evolving methods of <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> sequencing and functional characterization of the genome will enhance our understanding of the contribution by all functional genomic elements in both <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>endelian and complex phenotypes.<\/jats:p>","DOI":"10.1111\/cge.12272","type":"journal-article","created":{"date-parts":[[2013,9,5]],"date-time":"2013-09-05T17:54:43Z","timestamp":1378403683000},"page":"422-428","source":"Crossref","is-referenced-by-count":31,"title":["Pathogenic variants in non\u2010protein\u2010coding sequences"],"prefix":"10.1111","volume":"84","author":[{"given":"P","family":"Makrythanasis","sequence":"first","affiliation":[{"name":"Department of Genetic Medicine and Development University of Geneva Medical School Geneva 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