{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T06:05:35Z","timestamp":1743401135552,"version":"3.37.3"},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,5,21]],"date-time":"2015-05-21T00:00:00Z","timestamp":1432166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005972","name":"Deutsche Krebshilfe","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005972","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001861","name":"Swedish council for working life and social research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001861","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Genetics"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:p>We aimed to estimate the 15\u2010year and lifetime risks of contralateral breast cancer in breast cancer patients according to the age of diagnosis of the first cancer and the history of breast cancer in the mother. The risks of contralateral breast cancer were estimated for all 78,775 breast cancer patients in the Swedish Family\u2010Cancer Database (age at diagnosis of first breast cancer &lt;70 years). The risk of experiencing a contralateral breast cancer within 15 years of diagnosis was 8.4% [95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>): 8.1\u20138.7%] for women with an unaffected mother, was 12% (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 11\u201313%) for a woman with a mother with unilateral breast cancer and was 13% (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 9.5\u201317%) for women with a mother with bilateral breast cancer. In early\u2010onset diagnosed women (&lt;50 years) with an unaffected mother, the risk of contralateral breast cancer until age 80 was 23% (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 20\u201326%) and for late\u2010onset (50\u201369 years) diagnosed women it was 17% (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 14\u201321%). In a woman with a mother with an early\u2010onset unilateral breast cancer, risk of contralateral breast cancer by age 80 was 35% (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 25\u201346%). Women with a mother with early\u2010onset bilateral breast cancer had 31% (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 12\u201367%) lifetime risk of contralateral breast cancer. The risk of contralateral breast cancer is higher for daughters of breast cancer patients than for daughters of women without breast cancer. Maternal cancer history and age at onset of first breast cancer in women should be taken into account when counseling breast cancer patients about their risk of contralateral breast cancer.<\/jats:p>","DOI":"10.1111\/cge.12604","type":"journal-article","created":{"date-parts":[[2015,4,29]],"date-time":"2015-04-29T09:59:46Z","timestamp":1430301586000},"page":"332-335","source":"Crossref","is-referenced-by-count":11,"title":["The risk of contralateral breast cancer in daughters of women with and without breast cancer"],"prefix":"10.1111","volume":"89","author":[{"given":"S.A.","family":"Narod","sequence":"first","affiliation":[{"name":"Women's College Research Institute Women's College Hospital  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Kharazmi","sequence":"additional","affiliation":[{"name":"Division of Molecular Genetic Epidemiology German Cancer Research Center  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Fallah","sequence":"additional","affiliation":[{"name":"Division of Molecular Genetic Epidemiology German Cancer Research Center  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Sundquist","sequence":"additional","affiliation":[{"name":"Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden"},{"name":"Stanford Prevention Research Center Stanford University School of Medicine  Stanford CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hemminki","sequence":"additional","affiliation":[{"name":"Division of Molecular Genetic Epidemiology German Cancer Research Center  Heidelberg Germany"},{"name":"Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2014.3"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.43.2013"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116566"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.04.033"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.120"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67627-1"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/02841860152619214"},{"key":"e_1_2_6_9_1","unstructured":"StegmayrB. Cancer incidence in Sweden2006. The National Board of Health and Welfare. STATISTICS SWEDEN: HEALTH AND DISEASES 2007:16 SE\u2010106 30 STOCKHOLM 2007. Available at:http:\/\/www.socialstyrelsen.se\/lists\/artikelkatalog\/attachments\/9325\/2007\u201042\u201016_20074216.pdf"}],"container-title":["Clinical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcge.12604","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cge.12604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:10:46Z","timestamp":1696331446000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cge.12604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,21]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1111\/cge.12604"],"URL":"https:\/\/doi.org\/10.1111\/cge.12604","archive":["Portico"],"relation":{},"ISSN":["0009-9163","1399-0004"],"issn-type":[{"type":"print","value":"0009-9163"},{"type":"electronic","value":"1399-0004"}],"subject":[],"published":{"date-parts":[[2015,5,21]]}}}