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A systematic review was conducted by searching the published literature databases using available medical, physical, psychological, social databases and other sources. All studies that addressed pain in <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content>, published in peer\u2010reviewed journals were assessed. Of 351 search results, 18 articles satisfied the eligibility criteria. All studies were cross\u2010sectional and quantitative; no randomized controlled trials or intervention studies were found. Most studies had small sample sizes, low response rates and mainly dealt with other aspects of the diagnosis than pain. Only one article dealt mainly with pain. The research on chronic pain in <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content> is limited in size and quality. Despite these limitations, studies describe that the prevalence of pain in patients with <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content> is high, varying from 47 to 92% and affecting several anatomic sites. In addition, chronic pain limits daily function and few studies describe treatment options for pain in patients with <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content>. Research is needed to obtain more evidence\u2010based knowledge for developing more appropriate rehabilitation programs for people with <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/cge.12699","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T06:44:47Z","timestamp":1448520287000},"page":"647-658","source":"Crossref","is-referenced-by-count":32,"title":["Systematic review of chronic pain in persons with Marfan syndrome"],"prefix":"10.1111","volume":"89","author":[{"given":"G.","family":"Velvin","sequence":"first","affiliation":[{"name":"TRS National Resource Centre for Rare Disorders Sunnaas Rehabilitation Hospital  Nesodden Norway"},{"name":"Faculty of Social Sciences, Department of Social Work, Child Welfare and Social Policy Oslo and Akershus University College of Applied Sciences  Oslo 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