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The review process was conducted in accordance with the PRISMA\u2010ScR guidelines (Preferred Reporting Items for Systematic reviews and Meta\u2010Analyses Extension for Scoping Reviews). The selection of studies was based on criteria predefined in a review protocol. Twenty\u2010nine publications were included; 2 reviews, and 27 primary studies. Key information such as reference details, study characteristics, topics of interest, main findings and the study author's conclusion are presented in text and tables. Over the past decades, there has only been a slight increase in publications on adults with achondroplasia. The reported morbidity rates and prevalence of medical complications are often based on a few studies where the methodology and representativeness can be questioned. Studies on sleep\u2010related disorders and pregnancy\u2010related complications were lacking. Multicenter natural history studies have recently been initiated. Future studies should report in accordance to methodological reference standards, to strengthen the reliability and generalizability of the findings, and to increase the relevance for implementing in clinical practice.<\/jats:p>","DOI":"10.1111\/cge.13542","type":"journal-article","created":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T19:57:11Z","timestamp":1553716631000},"page":"179-197","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Current knowledge of medical complications in adults with achondroplasia: A scoping review"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2804-5783","authenticated-orcid":false,"given":"Svein O.","family":"Fredwall","sequence":"first","affiliation":[{"name":"Sunnaas Rehabilitation Hospital TRS National Resource Centre for Rare Disorders  Nesoddtangen Norway"},{"name":"Faculty of Medicine, Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grethe","family":"Maanum","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Institute of Clinical Medicine University of Oslo  Oslo Norway"},{"name":"Department of Research Sunnaas Rehabilitation Hospital  Nesoddtangen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Johansen","sequence":"additional","affiliation":[{"name":"Sunnaas Rehabilitation Hospital TRS National Resource Centre for Rare Disorders  Nesoddtangen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hildegun","family":"Snekkevik","sequence":"additional","affiliation":[{"name":"Department of Cognitive Rehabilitation Sunnaas Rehabilitation Hospital  Nesoddtangen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Savarirayan","sequence":"additional","affiliation":[{"name":"Victorian Clinical Genetics Service Murdoch Childrens Research Institute and University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingeborg B.","family":"Lidal","sequence":"additional","affiliation":[{"name":"Sunnaas Rehabilitation Hospital TRS National Resource Centre for Rare Disorders  Nesoddtangen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,22]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Achondroplasia","author":"Pauli RM","year":"1998"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/TACG.S51485"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-017-0347-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.189092"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.37394"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1440"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-018-0972-6"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000050"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/1364557032000119616"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-5908-5-69"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0850"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11832-011-0378-7"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638280701192857"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000000662"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-016-1455-7"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jspd.2015.08.003"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12890"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.12045"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-012-2126-x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.35373"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1758-0854.2010.01046.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3171\/2010.3.SPINE09629"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0142-6"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-10"},{"key":"e_1_2_9_26_1","unstructured":"JohansenH.Challenges of Being Short Statured. 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