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Full understanding of the genetic causes and potential inheritance patterns of both distinct FSHD types is essential: FSHD1 is an autosomal dominantly inherited repeat disorder, whereas FSHD2 is a digenic disorder. This has become even more relevant now that prenatal diagnosis and preimplantation genetic diagnosis options are available for FSHD1. Pregnancy and delivery outcomes in FSHD are usually favorable, but clinicians should be aware of the risks. We aim to provide clinicians with case\u2010based strategies for reproductive counseling in FSHD, as well as recommendations for pregnancy and delivery.<\/jats:p>","DOI":"10.1111\/cge.14031","type":"journal-article","created":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T11:36:55Z","timestamp":1627040215000},"page":"149-160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Facioscapulohumeral muscular dystrophy\u2014Reproductive counseling, pregnancy, and delivery in a complex multigenetic disease"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0412-0670","authenticated-orcid":false,"given":"Sanne C. 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