{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:46:49Z","timestamp":1787014009095,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Genetics"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>With advances in gene\u2010based therapies for heritable retinal diseases, primary eye care clinicians should be informed on ocular genetics topics. This cross\u2010sectional survey evaluated knowledge, attitudes, and concerns regarding genetic testing and gene therapy for retinal diseases among optometrists in Australia and New Zealand. Survey data included practitioner background, attitudes and practices towards genetic testing for monogenic inherited retinal disease (IRDs) and age\u2010related macular degeneration, and knowledge of ocular genetics and gene therapy. Responses were received from 516 optometrists between 1 April and 31 December 2022. Key perceived barriers to accessing genetic testing were lack of clarity on referral pathways (81%), cost (65%), and lack of treatment options if a genetic cause is identified (50%). Almost all respondents (98%) believed that ophthalmologists should initiate genetic testing for IRDs and fewer understood the role of genetic counsellors and clinical geneticists. This study found that optometrists in Australia and New Zealand have a high level of interest in ocular genetics topics. However, knowledge gaps include referral pathways and awareness of genetic testing and gene therapy outcomes. Addressing perceived barriers to access and promoting sharing of knowledge between interdisciplinary networks can set the foundation for genetic education agendas in primary eye care.<\/jats:p>","DOI":"10.1111\/cge.14415","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T22:59:01Z","timestamp":1691535541000},"page":"34-43","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Genetic testing and gene therapy in retinal diseases: Knowledge and perceptions of optometrists in\n                    <scp>Australia<\/scp>\n                    and\n                    <scp>New Zealand<\/scp>"],"prefix":"10.1111","volume":"105","author":[{"given":"Alexis Ceecee","family":"Britten\u2010Jones","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Dentistry and Health Sciences, Department of Optometry and Vision Sciences University of Melbourne  Parkville Victoria Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences, Department of Surgery (Ophthalmology) University of Melbourne  Parkville Victoria Australia"},{"name":"Centre for Eye Research Australia Royal Victorian Eye and Ear Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather G.","family":"Mack","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Dentistry and Health Sciences, Department of Surgery (Ophthalmology) University of Melbourne  Parkville Victoria Australia"},{"name":"Centre for Eye Research Australia Royal Victorian Eye and Ear Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4185-3267","authenticated-orcid":false,"given":"Andrea L.","family":"Vincent","sequence":"additional","affiliation":[{"name":"Eye Department, Greenlane Clinical Centre Auckland District Health Board  Auckland New Zealand"},{"name":"Faculty of Medical and Health Sciences, Department of Ophthalmology, New Zealand National Eye Centre The University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa J.","family":"Hill","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences, Institute of Clinical Sciences University of Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas L.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Dentistry and Health Sciences, Department of Surgery (Ophthalmology) University of Melbourne  Parkville Victoria Australia"},{"name":"Centre for Eye Research Australia Royal Victorian Eye and Ear Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren N.","family":"Ayton","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Dentistry and Health Sciences, Department of Optometry and Vision Sciences University of Melbourne  Parkville Victoria Australia"},{"name":"Centre for Eye Research Australia Royal Victorian Eye and Ear Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,8]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"DaigerSP RossiterBJF GreenbergJ ChristoffelsA HideW.RetNet \u2013 Retinal information network. 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