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The majority of patients reported on in this sample are characterized by an inverted\u2010duplication deletion rearrangement, but deletions, duplications, and mosaic ring changes in 8p result in similar phenotype. In this report, we add to the phenotypic and functional description of these patients according to their specific chromosomal rearrangement, share neuro\u2010psychometric values, and propose surveillance care guidelines for caregivers and medical providers of patients with Chromosome 8p Syndromes. Observations from clinical experience with 24 patients seen at our 8p\u2010dedicated Multi\u2010Disciplinary Neurogenetics program are shared.<\/jats:p>","DOI":"10.1111\/cge.14626","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T23:44:37Z","timestamp":1728603877000},"page":"169-178","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Chromosome 8p Syndromes Clinical Presentation and Management Guidelines"],"prefix":"10.1111","volume":"107","author":[{"given":"Kourtney","family":"Santucci","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina E.","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Angione","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Bennink","sequence":"additional","affiliation":[{"name":"Rehabilitation and Therapy Service Line Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gerk","sequence":"additional","affiliation":[{"name":"Rehabilitation and Therapy Service Line Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drew","family":"Mancini","sequence":"additional","affiliation":[{"name":"Rehabilitation and Therapy Service Line Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Stringfellow","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristen","family":"Dinkel","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Demarest","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea S.","family":"Miele","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita","family":"Saenz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine\/Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/319506"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41436\u2010021\u201001270\u20102"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.14096"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10519\u2010011\u20109447\u20104"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci10070451"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.36879"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2010.10.003"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.35767"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000494796"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13039\u2010014\u20100094\u20103"},{"issue":"4","key":"e_1_2_8_12_1","first-page":"241","article-title":"Duplication\u2010Deficiency of the Short Arm of Chromosome 8 Following Artificial Insemination","volume":"19","author":"Weleber R. 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