{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T07:55:16Z","timestamp":1771660516820,"version":"3.50.1"},"reference-count":17,"publisher":"Computers, Materials and Continua (Tech Science Press)","issue":"6","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":991,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1111\/chd.12022","type":"journal-article","created":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T11:56:01Z","timestamp":1355486161000},"page":"520-526","source":"Crossref","is-referenced-by-count":36,"title":["High-sensitivity Troponin T Is Associated with Poor Outcome in Adults with Pulmonary Arterial Hypertension due to Congenital Heart Disease"],"prefix":"10.32604","volume":"8","author":[{"given":"Mark J.","family":"Schuuring","sequence":"first","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"},{"name":"Interuniversity Cardiology Institute of the Netherlands; Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annelieke C.M.J.","family":"van Riel","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"},{"name":"Interuniversity Cardiology Institute of the Netherlands; Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen C.","family":"Vis","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marielle G.","family":"Duffels","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan P.","family":"van Straalen","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry; Academic Medical Center; Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Matthijs","family":"Boekholdt","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan G.P.","family":"Tijssen","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara J.M.","family":"Mulder","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berto J.","family":"Bouma","sequence":"additional","affiliation":[{"name":"Department of Cardiology; Academic Medical Center; Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"17807","published-online":{"date-parts":[[2012,12,14]]},"reference":[{"key":"10.1111\/chd.12022-BIB0001|chd12022-cit-0001","first-page":"359","article-title":"Adult patients with pulmonary arterial hypertension due to congenital heart disease: a review on advanced medical treatment with bosentan","volume":"6","author":"Schuuring","year":"2010","journal-title":"Ther Clin Risk Manag."},{"key":"10.1111\/chd.12022-BIB0002|chd12022-cit-0002","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ijcard.2006.09.017","article-title":"Pulmonary arterial hypertension in congenital heart disease: an epidemiologic perspective from a Dutch registry","volume":"120","author":"Duffels","year":"2007","journal-title":"Int J Cardiol."},{"key":"10.1111\/chd.12022-BIB0003|chd12022-cit-0003","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1093\/eurheartj\/ehp297","article-title":"Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)","volume":"30","author":"Gali\u00e8","year":"2009","journal-title":"Eur Heart J."},{"key":"10.1111\/chd.12022-BIB0004|chd12022-cit-0004","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s12471-011-0220-3","article-title":"Recent progress in treatment of pulmonary arterial hypertension due to congenital heart disease","volume":"19","author":"Schuuring","year":"2011","journal-title":"Neth Heart J."},{"key":"10.1111\/chd.12022-BIB0005|chd12022-cit-0005","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1747-0803.2007.00104.x","article-title":"Pulmonary arterial hypertension associated with a congenital heart defect: advanced medium-term medical treatment stabilizes clinical condition","volume":"2","author":"Duffels","year":"2007","journal-title":"Congenit Heart Dis."},{"key":"10.1111\/chd.12022-BIB0006|chd12022-cit-0006","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1161\/01.CIR.0000084544.54513.E2","article-title":"Detectable serum cardiac troponin T as a marker of poor prognosis among patients with chronic precapillary pulmonary hypertension","volume":"108","author":"Torbicki","year":"2003","journal-title":"Circulation."},{"key":"10.1111\/chd.12022-BIB0007|chd12022-cit-0007","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1042\/CS20100014","article-title":"High-sensitive troponin T: a novel biomarker for prognosis and disease severity in patients with pulmonary arterial hypertension","volume":"119","author":"Filusch","year":"2010","journal-title":"Clin Sci."},{"key":"10.1111\/chd.12022-BIB0008|chd12022-cit-0008","article-title":"Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study","author":"Li","year":"2012","journal-title":"Int J Cardiovasc Imaging."},{"key":"10.1111\/chd.12022-BIB0009|chd12022-cit-0009","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1309\/LR7FC0LUGLHT8X6J","article-title":"The effect of freezing and long-term storage on the stability of cardiac troponin T","volume":"128","author":"Basit","year":"2007","journal-title":"Am J Clin Pathol."},{"key":"10.1111\/chd.12022-BIB0010|chd12022-cit-0010","unstructured":"Roche Diagnostics Troponin T STAT kit [package insert] 2002"},{"key":"10.1111\/chd.12022-BIB0011|chd12022-cit-0011","article-title":"Treatment of segmental pulmonary artery hypertension in adults with congenital heart disease","author":"Schuuring","year":"2011","journal-title":"Int J Cardiol."},{"key":"10.1111\/chd.12022-BIB0012|chd12022-cit-0012","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/ejechocard\/jen308","article-title":"Duration of right ventricular contraction predicts the efficacy of bosentan treatment in patients with pulmonary hypertension","volume":"10","author":"Duffels","year":"2009","journal-title":"Eur J Echocardiogr."},{"key":"10.1111\/chd.12022-BIB0013|chd12022-cit-0013","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1136\/heart.88.4.323","article-title":"Prognostic importance of right ventricular dysfunction","volume":"88","author":"Bleasdale","year":"2002","journal-title":"Heart."},{"key":"10.1111\/chd.12022-BIB0014|chd12022-cit-0014","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1515\/cclm.2011.251","article-title":"High-sensitive troponin T in chronic heart failure correlates with severity of symptoms, left ventricular dysfunction and prognosis independently from N-terminal pro-b-type natriuretic peptide","volume":"49","author":"Jungbauer","year":"2011","journal-title":"Clin Chem Lab Med."},{"key":"10.1111\/chd.12022-BIB0015|chd12022-cit-0015","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1161\/CIRCULATIONAHA.111.023937","article-title":"Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction","volume":"124","author":"Reichlin","year":"2011","journal-title":"Circulation."},{"key":"10.1111\/chd.12022-BIB0016|chd12022-cit-0016","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1161\/CIRCULATIONAHA.106.630715","article-title":"Bosentan Randomized Trial of Endothelin Antagonist Therapy-5 (BREATHE-5) Investigator. Bosentan therapy in patients with Eisenmenger Syndrome: a multicenter, double-blind, randomized, placebo-controlled study","volume":"114","author":"Gali\u00e8","year":"2006","journal-title":"Circulation."},{"key":"10.1111\/chd.12022-BIB0017|chd12022-cit-0017","article-title":"Prolonged beneficial effect of bosentan treatment and 4-year survival rates in adult patients with pulmonary arterial hypertension associated with congenital heart disease","author":"Vis","year":"2011","journal-title":"Int J Cardiol."}],"container-title":["Congenital Heart Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fchd.12022","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T22:03:23Z","timestamp":1588025003000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1111\/chd.12022"}},"subtitle":["Troponin T and Survival in CHD-PAH"],"short-title":[],"issued":{"date-parts":[[2012,12,14]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,11]]}},"URL":"https:\/\/doi.org\/10.1111\/chd.12022","relation":{},"ISSN":["1747-079X"],"issn-type":[{"value":"1747-079X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12,14]]}}}