{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:31:33Z","timestamp":1791869493024,"version":"4.3.4"},"reference-count":44,"publisher":"Tech Science Press","issue":"4","license":[{"start":{"date-parts":[[2017,6,5]],"date-time":"2017-06-05T00:00:00Z","timestamp":1496620800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,6,5]],"date-time":"2017-06-05T00:00:00Z","timestamp":1496620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Congenital Heart Disease"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1111\/chd.12467","type":"journal-article","created":{"date-parts":[[2017,6,5]],"date-time":"2017-06-05T01:26:40Z","timestamp":1496626000000},"page":"430-434","source":"Crossref","is-referenced-by-count":16,"title":["Mitral valve prolapse and Marfan syndrome"],"prefix":"10.32604","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6911-9320","authenticated-orcid":false,"given":"Amitabh","family":"Thacoor","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery; Leeds General Infirmary; Great George Street Leeds United KIngdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17807","published-online":{"date-parts":[[2017,6,5]]},"reference":[{"issue":"2","key":"10.1111\/chd.12467-BIB0001|chd12467-cit-0002","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0002-9149(00)80066-1","article-title":"Life expectancy in the Marfan syndrome","volume":"75","author":"Silverman","year":"1995","journal-title":"Am J Cardiol."},{"key":"10.1111\/chd.12467-BIB0002|chd12467-cit-0003","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/sj.ejhg.5201851","article-title":"Marfan syndrome: clinical diagnosis and management","volume":"15","author":"Dean","year":"2007","journal-title":"Eur J Hum Genet."},{"key":"10.1111\/chd.12467-BIB0003|chd12467-cit-0004","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1146\/annurev.med.51.1.481","article-title":"The Marfan syndrome","volume":"51","author":"Pyeritz","year":"2000","journal-title":"Annu Rev Med."},{"issue":"5","key":"10.1111\/chd.12467-BIB0004|chd12467-cit-0005","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.avsg.2008.04.005","article-title":"Ten-year epidemiological review of in-hospital patients with Marfan syndrome","volume":"22","author":"Chan","year":"2008","journal-title":"Ann Vasc Surg."},{"issue":"11","key":"10.1111\/chd.12467-BIB0005|chd12467-cit-0006","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1172\/JCI23701","article-title":"Marfan syndrome and mitral valve prolapse","volume":"114","author":"Weyman","year":"2004","journal-title":"J Clin Invest."},{"key":"10.1111\/chd.12467-BIB0006|chd12467-cit-0007","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/0002-9343(83)91070-7","article-title":"Mitral valve dysfunction in the Marfan syndrome. Clinical and echocardiographic study of prevalence and natural history","volume":"74","author":"Pyeritz","year":"1983","journal-title":"Am J Med."},{"key":"10.1111\/chd.12467-BIB0007|chd12467-cit-0008","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1161\/01.CIR.52.4.651","article-title":"Aortic root dilatation and mitral valve prolapse in Marfan's syndrome: an ECHOCARDIOgraphic study","volume":"52","author":"Brown","year":"1975","journal-title":"Circulation."},{"key":"10.1111\/chd.12467-BIB0008|chd12467-cit-0009","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0002-9149(83)90138-8","article-title":"The Marfan syndrome in early childhood: analysis of 15 patients diagnosed at less than 4 years of age","volume":"52","author":"Sisk","year":"1983","journal-title":"Am J Cardiol."},{"key":"10.1111\/chd.12467-BIB0009|chd12467-cit-0010","first-page":"1179","article-title":"The clinical course and echocardiographic features of Marfan's syndrome in childhood","volume":"141","author":"Geva","year":"1987","journal-title":"Am J Dis Child."},{"key":"10.1111\/chd.12467-BIB0010|chd12467-cit-0011","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1161\/01.CIR.47.3.587","article-title":"Cardiac manifestations of Marfan syndrome in infancy and childhood","volume":"47","author":"Phornphutkul","year":"1973","journal-title":"Circulation."},{"key":"10.1111\/chd.12467-BIB0011|chd12467-cit-0012","first-page":"888","article-title":"Diagnosis and management of infantile Marfan syndrome","volume":"86","author":"Morse","year":"1990","journal-title":"Pediatrics."},{"key":"10.1111\/chd.12467-BIB0012|chd12467-cit-0013","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1161\/01.CIR.54.1.3","article-title":"Mitral valve prolapse","volume":"54","author":"Devereux","year":"1976","journal-title":"Circulation."},{"key":"10.1111\/chd.12467-BIB0013|chd12467-cit-0014","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0002-8703(63)90375-2","article-title":"The significance of the systolic murmurs","volume":"66","author":"Barlow","year":"1963","journal-title":"Am Heart J."},{"issue":"Suppl. III","key":"10.1111\/chd.12467-BIB0014|chd12467-cit-0015","first-page":"45","article-title":"Echocardiographic recognition of mitral valve prolapse","volume":"42","author":"Shah","year":"1970","journal-title":"Circulation."},{"key":"10.1111\/chd.12467-BIB0015|chd12467-cit-0016","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1161\/01.CIR.43.4.503","article-title":"Use of echocardiography in patients with prolapsed mitral valve","volume":"43","author":"Dillon","year":"1971","journal-title":"Circulation."},{"key":"10.1111\/chd.12467-BIB0016|chd12467-cit-0017","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1056\/NEJM197104012841303","article-title":"Echocardiographic patterns in patients with the syndrome of systolic click and late systolic murmur","volume":"284","author":"Kerber","year":"1971","journal-title":"N Engl J Med."},{"key":"10.1111\/chd.12467-BIB0017|chd12467-cit-0018","first-page":"143","article-title":"Mitral valve prolapse patients in a local population","volume":"37","author":"Yeo","year":"1996","journal-title":"Singapore Med J."},{"issue":"2","key":"10.1111\/chd.12467-BIB0018|chd12467-cit-0019","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1148\/radiol.2541090393","article-title":"Cardiac CT angiography for the diagnosis of mitral valve prolapse: comparison with echocardiography","volume":"254","author":"Feuchtner","year":"2010","journal-title":"Radiology."},{"key":"10.1111\/chd.12467-BIB0019|chd12467-cit-0020","doi-asserted-by":"crossref","first-page":"A151.E1414","DOI":"10.1016\/S0735-1097(10)61415-5","article-title":"Anatomical classification of mitral valve prolapse using volumetric analysis of real-time three-dimensional echocardiographic images","volume":"55","author":"Chandra","year":"2010","journal-title":"J Am Coll Cardiol."},{"key":"10.1111\/chd.12467-BIB0020|chd12467-cit-0021","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/S0735-1097(98)90059-6","article-title":"Reconsideration of echocardiographic standards for mitral valve prolapse: lack of association between leaflet displacement isolated to the apical four chamber view and independent echocardiographic evidence of abnormality","volume":"11","author":"Levine","year":"1988","journal-title":"J Am Coll Cardiol."},{"issue":"2","key":"10.1111\/chd.12467-BIB0021|chd12467-cit-0022","first-page":"73","article-title":"Mitral valve prolapse: time for a fresh look","volume":"2","author":"Playford","year":"2001","journal-title":"Rev Cardiovasc Med."},{"issue":"9458","key":"10.1111\/chd.12467-BIB0022|chd12467-cit-0023","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0140-6736(05)70275-0","article-title":"Mitral valve prolapse","volume":"365","author":"Hayek","year":"2005","journal-title":"Lancet."},{"key":"10.1111\/chd.12467-BIB0023|chd12467-cit-0024","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1161\/01.CIR.78.1.10","article-title":"Lifetime risk for patients with mitral valve prolapse of developing severe valve regurgitation requiring surgery","volume":"78","author":"Wilcken","year":"1988","journal-title":"Circulation."},{"key":"10.1111\/chd.12467-BIB0024|chd12467-cit-0025","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0002-9149(85)90315-7","article-title":"Mitral valve prolapse and ruptured chordae tendinae","volume":"55","author":"Jeresaty","year":"1985","journal-title":"Am J Cardiol."},{"key":"10.1111\/chd.12467-BIB0025|chd12467-cit-0026","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0002-8703(85)90543-5","article-title":"Mitral valve prolapse and bacterial endocarditis: when is antibiotic prophylaxis necessary?","volume":"109","author":"Hickey","year":"1985","journal-title":"Am Heart J."},{"issue":"11","key":"10.1111\/chd.12467-BIB0026|chd12467-cit-0027","first-page":"1097","article-title":"Sudden death in young people with apparently isolated mitral valve prolapse","volume":"27","author":"Corrado","year":"1997","journal-title":"G Ital Cardiol."},{"key":"10.1111\/chd.12467-BIB0027|chd12467-cit-0028","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/sj.ejhg.5200876","article-title":"Marfan syndrome in the third Millennium","volume":"10","author":"Collod-B\u00e9roud","year":"2002","journal-title":"Eur J Hum Genet."},{"key":"10.1111\/chd.12467-BIB0028|chd12467-cit-0029","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/ng0303-331","article-title":"Fibrillin controls TGF-\u03b2 activation","volume":"33","author":"Kaartinen","year":"2003","journal-title":"Nat Genet."},{"issue":"5770","key":"10.1111\/chd.12467-BIB0029|chd12467-cit-0030","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1126\/science.1124287","article-title":"Losartan, an AT1 antagonist, prevents aortic aneurysm in a\u00a0mouse model of Marfan syndrome","volume":"312","author":"Habashi","year":"2006","journal-title":"Science."},{"key":"10.1111\/chd.12467-BIB0030|chd12467-cit-0031","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/352337a0","article-title":"Marfan syndrome cause by a recurrent de novo missense mutation in the fibrillin gene","volume":"352","author":"Dietz","year":"1991","journal-title":"Nature."},{"key":"10.1111\/chd.12467-BIB0031|chd12467-cit-0032","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1172\/JCI200422715","article-title":"TGF-\u03b2-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome","volume":"114","author":"Ng","year":"2004","journal-title":"J Clin Invest."},{"key":"10.1111\/chd.12467-BIB0032|chd12467-cit-0033","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1136\/hrt.40.5.468","article-title":"The floppy mitral valve. Study of incidence, pathology, and complications in surgical, necropsy and forensic material","volume":"40","author":"Davies","year":"1978","journal-title":"Br Heart J."},{"key":"10.1111\/chd.12467-BIB0033|chd12467-cit-0034","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/1054773806295240","article-title":"Medication use and symptoms in individuals with mitral valve prolapse syndrome","volume":"16","author":"Scordo","year":"2007","journal-title":"Clin Nurs Res."},{"issue":"4","key":"10.1111\/chd.12467-BIB0034|chd12467-cit-0035","first-page":"305","article-title":"Mitral valve prolapse: causes","volume":"111","author":"Desvereux","year":"1989","journal-title":"Clin Manifest Manage."},{"key":"10.1111\/chd.12467-BIB0035|chd12467-cit-0036","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/heart.87.1.79","article-title":"Timing of mitral valve surgery","volume":"87","author":"Enriquez-Sarano","year":"2002","journal-title":"Heart."},{"key":"10.1111\/chd.12467-BIB0036|chd12467-cit-0037","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0003-4975(98)00314-2","article-title":"Surgical management of mitral regurgitation associated with Marfan's syndrome","volume":"66","author":"Fuzellier","year":"1998","journal-title":"Ann Thorac Surg."},{"key":"10.1111\/chd.12467-BIB0037|chd12467-cit-0038","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0022-5223(19)42938-3","article-title":"Surgical correction of mitral insufficiency in Marfan's syndrome","volume":"55","author":"Sirak","year":"1967","journal-title":"J Thorac Cardiovasc Surg."},{"key":"10.1111\/chd.12467-BIB0038|chd12467-cit-0039","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/S0022-5223(94)70328-0","article-title":"Mitral valve operation in patients with the Marfan syndrome","volume":"107","author":"Gillinov","year":"1994","journal-title":"J Thorac Cardiovasc."},{"key":"10.1111\/chd.12467-BIB0039|chd12467-cit-0040","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.athoracsur.2005.08.055","article-title":"Mitral valve surgery in the adult Marfan syndrome patient","volume":"81","author":"Bhudia","year":"2006","journal-title":"Ann Thorac Surg."},{"key":"10.1111\/chd.12467-BIB0040|chd12467-cit-0041","doi-asserted-by":"crossref","first-page":"I-1","DOI":"10.1161\/hc37t1.094903","article-title":"Very long-term survival and durability of mitral valve repair for mitral valve prolapse","volume":"104","author":"Mohty","year":"2001","journal-title":"Circulation."},{"issue":"11 Suppl 1","key":"10.1111\/chd.12467-BIB0041|chd12467-cit-0042","doi-asserted-by":"crossref","first-page":"S243","DOI":"10.1161\/CIRCULATIONAHA.112.000113","article-title":"Mitral valve disease in patients with Marfan syndrome undergoing aortic root replacement","volume":"128","author":"Kunkala","year":"2013","journal-title":"Circulation."},{"issue":"18","key":"10.1111\/chd.12467-BIB0042|chd12467-cit-0043","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/0002-9149(90)90979-B","article-title":"Two-dimensional and Doppler echocardiographic and pathologic characteristics of the infantile Marfan syndrome","volume":"65","author":"Geva","year":"1990","journal-title":"Am J Cardiol."},{"issue":"1","key":"10.1111\/chd.12467-BIB0043|chd12467-cit-0044","doi-asserted-by":"crossref","first-page":"7","DOI":"10.5090\/kjtcs.2015.48.1.7","article-title":"Surgical management of mitral regurgitation in patients with Marfan syndrome during infancy and early childhood","volume":"48","author":"Kim","year":"2015","journal-title":"Korean J Thorac Cardiovasc Surg."},{"issue":"1","key":"10.1111\/chd.12467-BIB0044|chd12467-cit-0045","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jaad.2008.03.039","article-title":"Clinical significance of cutaneous proteoglycan (mucin) infiltration in patients with mitral valve prolapse","volume":"59","author":"Romanelli","year":"2008","journal-title":"J Am Acad Dermatol."}],"container-title":["Congenital Heart Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fchd.12467","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.techscience.com\/uploads\/attached\/file\/20200521\/20200521035445_46210.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T13:23:44Z","timestamp":1733491424000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.techscience.com\/chd\/v12n4\/39174"}},"subtitle":["THACOOR"],"short-title":[],"issued":{"date-parts":[[2017,6,5]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,7]]}},"URL":"https:\/\/doi.org\/10.1111\/chd.12467","archive":["Portico"],"relation":{},"ISSN":["1747-079X"],"issn-type":[{"value":"1747-079X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6,5]]}}}