{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T01:09:25Z","timestamp":1793322565766,"version":"4.5.0"},"reference-count":32,"publisher":"Tech Science Press","license":[{"start":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T00:00:00Z","timestamp":1544572800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Congenital Heart Disease"],"DOI":"10.1111\/chd.12727","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T13:12:16Z","timestamp":1544620336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["What is a hemodynamically significant PDA in preterm infants?"],"prefix":"10.32604","author":[{"given":"Jennifer L.","family":"Shepherd","sequence":"first","affiliation":[{"name":"Fetal and Neonatal Institute, Division of Neonatology, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine University of Southern California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6262-3666","authenticated-orcid":false,"given":"Shahab","family":"Noori","sequence":"additional","affiliation":[{"name":"Fetal and Neonatal Institute, Division of Neonatology, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine University of Southern California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17807","published-online":{"date-parts":[[2018,12,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1440-1754.1994.tb00689.x","article-title":"A blinded comparison of clinical and echocardiographic evaluation of the preterm infant for patent ductus arteriosus","volume":"30","author":"Skelton R","year":"1994","journal-title":"J Paediatr Child Health"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"F36","DOI":"10.1136\/fn.77.1.F36","article-title":"Echocardiographic assessment of patent ductus arteriosus shunt flow pattern in premature infants","volume":"77","author":"Su BH","year":"1997","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"e_1_2_9_4_1","unstructured":"Practical Neonatal Echocardiography 2019 McGraw\u2010Hill New York S Noori B Siassi S Noori R Acherman P Wong Patent ductus arteriosus 163 178"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"F35","DOI":"10.1136\/adc.2010.207233","article-title":"Echocardiographic assessment of ductal significance: retrospective comparison of two methods","volume":"97","author":"Cond\u00f2 M","year":"2012","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1001\/jamapediatrics.2015.0987","article-title":"Diagnosis, evaluation, and management of patent ductus arteriosus in preterm neonates","volume":"169","author":"Jain A","year":"2015","journal-title":"JAMA Pediatr"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0022-3476(81)80408-8","article-title":"The effect of patent ductus arteriosus on flow velocity in the anterior cerebral arteries: ductal steal in the premature newborn infant","volume":"99","author":"Perlman JM","year":"1981","journal-title":"J Pediatr"},{"key":"e_1_2_9_8_1","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0022-3476(82)80715-4","article-title":"Abnormal cerebral blood flow patterns in preterm infants with a large patent ductus arteriosus","volume":"101","author":"Martin CG","year":"1982","journal-title":"J Pediatr"},{"key":"e_1_2_9_9_1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/s004310051125","article-title":"A patent ductus arteriosus is associated with reduced middle cerebral artery blood flow velocity","volume":"158","author":"Weir FJ","year":"1999","journal-title":"Eur J Pediatr"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0022-3476(94)70210-1","article-title":"Effects of patent ductus arteriosus on left ventricular output and organ blood flows in preterm infants with respiratory distress syndrome treated with surfactant","volume":"125","author":"Shimada S","year":"1994","journal-title":"J Pediatr"},{"key":"e_1_2_9_11_1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/jp.2010.200","article-title":"Regional tissue oxygenation in preterm born infants in association with echocardiographically significant patent ductus arteriosus","volume":"31","author":"Petrova A","year":"2011","journal-title":"J Perinatol"},{"key":"e_1_2_9_12_1","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/pr.2016.148","article-title":"Near\u2010infrared spectroscopy for detection of a significant patent ductus arteriosus","volume":"80","author":"Chock VY","year":"2016","journal-title":"Pediatr Res"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000445101","article-title":"A hemodynamically significant patent ductus arteriosus does not affect cerebral or renal tissue oxygenation in preterm infants","volume":"110","author":"van der Laan ME","year":"2016","journal-title":"Neonatology"},{"key":"e_1_2_9_14_1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000475933","article-title":"Abdominal near\u2010infrared spectroscopy detects low mesenteric perfusion early in preterm infants with hemodynamic significant ductus arteriosus","volume":"112","author":"Ledo A","year":"2017","journal-title":"Neonatology"},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s12887-018-1054-6","article-title":"Prospective observational study on assessing the hemodynamic relevance of patent ductus arteriosus with frequency domain near\u2010infrared spectroscopy","volume":"18","author":"Schwarz CE","year":"2018","journal-title":"BMC Pediatr"},{"key":"e_1_2_9_16_1","doi-asserted-by":"crossref","first-page":"F424","DOI":"10.1136\/adc.2007.118117","article-title":"Towards rational management of the patent ductus arteriosus: the need for disease staging","volume":"92","author":"McNamara PJ","year":"2007","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"1","key":"e_1_2_9_17_1","first-page":"S14\u201018","article-title":"Patent ductus arteriosus: pathophysiology and management","volume":"26","author":"Hermes\u2010DeSantis ER","year":"2006","journal-title":"J Perinatol"},{"key":"e_1_2_9_18_1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1542\/peds.2009-3506","article-title":"Patent ductus arteriosus of the preterm infant","volume":"125","author":"Hamrick S","year":"2010","journal-title":"Pediatrics"},{"key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/jp.2009.60","article-title":"Effects of low oxygen saturation limits on the ductus arteriosus in extremely low birth weight infants","volume":"29","author":"Noori S","year":"2009","journal-title":"J Perinatol"},{"key":"e_1_2_9_20_1","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1542\/peds.2005-1528","article-title":"Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1000 grams or less","volume":"117","author":"Koch J","year":"2006","journal-title":"Pediatrics"},{"issue":"2","key":"e_1_2_9_21_1","doi-asserted-by":"crossref","first-page":"e20164258","DOI":"10.1542\/peds.2016-4258","article-title":"Spontaneous closure of patent ductus arteriosus in infants \u22641500 g","volume":"140","author":"Semberova J","year":"2017","journal-title":"Pediatrics"},{"key":"e_1_2_9_22_1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1542\/peds.66.1.42","article-title":"Intraventricular hemorrhage: a prospective evaluation of etiopathogenesis","volume":"66","author":"Dykes FD","year":"1980","journal-title":"Pediatrics"},{"key":"e_1_2_9_23_1","doi-asserted-by":"crossref","first-page":"F183","DOI":"10.1136\/fn.75.3.F183","article-title":"Early ductal shunting and intraventricular haemorrhage in ventilated preterm infants","volume":"75","author":"Evans N","year":"1996","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"e_1_2_9_24_1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.siny.2015.02.004","article-title":"Hemodynamic antecedents of peri\/intraventricular hemorrhage in very preterm neonates","volume":"20","author":"Noori S","year":"2015","journal-title":"Semin Fetal Neonatal Med"},{"key":"e_1_2_9_25_1","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.pedneo.2016.01.001","article-title":"Circulatory management focusing on preventing intraventricular hemorrhage and pulmonary hemorrhage in preterm infants","volume":"57","author":"Su B\u2010H","year":"2016","journal-title":"Pediatr Neonatol"},{"key":"e_1_2_9_26_1","doi-asserted-by":"crossref","first-page":"F99","DOI":"10.1136\/archdischild-2013-304695","article-title":"A randomised placebo\u2010controlled trial of early treatment of the patent ductus arteriosus","volume":"99","author":"Kluckow M","year":"2014","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"e_1_2_9_27_1","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1038\/jp.2010.97","article-title":"Patent ductus arteriosus in the preterm infant: to treat or not to treat?","volume":"30","author":"Noori S","year":"2010","journal-title":"J Perinatol"},{"key":"e_1_2_9_28_1","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/j.jpeds.2015.09.028","article-title":"A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge","volume":"167","author":"El\u2010Khuffash A","year":"2015","journal-title":"J Pediatr"},{"key":"e_1_2_9_29_1","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/j.jpeds.2015.03.012","article-title":"Association between hemodynamically significant patent ductus arteriosus and bronchopulmonary dysplasia","volume":"166","author":"Schena F","year":"2015","journal-title":"J Pediatr"},{"key":"e_1_2_9_30_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jpeds.2017.03.021","article-title":"Prophylactic indomethacin compared with delayed conservative management of the patent ductus arteriosus in extremely preterm infants: effects on neonatal outcomes","volume":"187","author":"Liebowitz M","year":"2017","journal-title":"J Pediatr"},{"key":"e_1_2_9_31_1","doi-asserted-by":"crossref","first-page":"F133","DOI":"10.1136\/adc.2010.185967","article-title":"Troponin T, N\u2010terminal pro natriuretic peptide and a patent ductus arteriosus scoring system predict death before discharge or neurodevelopmental outcome at 2 years in preterm infants","volume":"96","author":"El\u2010Khuffash AF","year":"2011","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"e_1_2_9_32_1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s00431-012-1851-0","article-title":"Functional echocardiography in staging for ductal disease severity: role in predicting outcomes","volume":"172","author":"Sehgal A","year":"2013","journal-title":"Eur J Pediatr"},{"key":"e_1_2_9_33_1","first-page":"659","article-title":"A clinical scoring system to predict the development of bronchopulmonary dysplasia","volume":"32","author":"Gursoy T","year":"2015","journal-title":"Am J Perinatol"}],"container-title":["Congenital Heart Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/chd.12727","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/chd.12727","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.techscience.com\/uploads\/attached\/file\/20200427\/20200427064035_89027.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T18:25:51Z","timestamp":1733509551000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.techscience.com\/chd\/v14n1\/38750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,12]]},"references-count":32,"alternative-id":["10.1111\/chd.12727"],"URL":"https:\/\/doi.org\/10.1111\/chd.12727","archive":["Portico"],"relation":{},"ISSN":["1747-079X","1747-0803"],"issn-type":[{"value":"1747-079X","type":"print"},{"value":"1747-0803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,12]]},"article-number":"chd.12727"}}