{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:32:51Z","timestamp":1791379971006,"version":"4.3.3"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T00:00:00Z","timestamp":1374624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In three former reports, the present team has presented the 1\u2010year outcome of four different treatment procedures handling the edentulous mandible; that is, two\u2010stage and one\u2010stage surgery with turned <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>r\u00e5nemark <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ystem\u00ae (<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>obel <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>iocare <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>othenburg, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>weden) implants (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup 1 and 2) and one\u2010stage surgery using either 5 or 4 <jats:styled-content style=\"fixed-case\">TiU<\/jats:styled-content>nite\u2122 (<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>obel <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>iocare <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>othenburg, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>weden) implants (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup 3 and 4).<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of the present investigation was to follow up these patients for a period of 5 years with regard to implant\/prosthesis cumulative survival rates, marginal bone loss calculations, clinical complications, and results related to age at surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A total of 385 patients, provided with 1,838 implants, were originally included in the four patient groups. All patients received fixed prostheses. The overall majority of patients had each five implants placed. Radiographs were obtained at prosthesis delivery, at the 1 and 5\u2010year follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1,230 implants in 259 patients (67%) were possible to follow up for 5 years. Implant <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>umulative <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>urvival <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>ates (<jats:styled-content style=\"fixed-case\">CSR<\/jats:styled-content>) in 5 years for <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roups 1\u20134 were 99.7, 97.0, 98.5, and 98.6%. The corresponding prosthesis treatment <jats:styled-content style=\"fixed-case\">CSR<\/jats:styled-content> was 100, 99.3, 98.5, and 98.6%, respectively. Significantly, more patients (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) lost turned implants after one\u2010stage surgery (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup 2). Frequency distributions of implants revealed that &gt;1.2\u2009mm bone loss was observed around 75 implants (6.4%). The moderately rough central (midline) implant showed more bone loss than other placed implants (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup 3; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). The youngest half of included patients at surgery (<jats:styled-content style=\"fixed-case\">Y<\/jats:styled-content>oungest<jats:sup>50%<\/jats:sup>; <jats:italic>n<\/jats:italic>\u2009=\u2009193) presented significantly higher mortality than older patients as well as compared to normal population (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Patients in the Younger<jats:sup>50%<\/jats:sup> group showed also an association to patients with complete loss of all implants and patients with most implants with obvious bone loss after 5 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>All four treatment procedures served well during the 5 years of follow\u2010up and only eight patients (2.1%) were complete failures or showed obvious bone loss (&gt;1.8\u2009mm) at several implants (&gt;2 implants), mostly observed in younger patients. The few complications in relation to implant failure and\/or obvious bone loss could be associated to both <jats:italic>local impact<\/jats:italic> factors (surface, implant site, surgical protocol) as well as to <jats:italic>host response<\/jats:italic> factors (systemic health).<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.12116","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T18:47:48Z","timestamp":1374691668000},"page":"413-424","source":"Crossref","is-referenced-by-count":38,"title":["Rehabilitation of Edentulous Mandibles by Means of Osseointegrated Implants: A 5\u2010Year Follow\u2010Up Study on One or Two\u2010Stage Surgery, Number of Implants, Implant Surfaces, and Age at Surgery"],"prefix":"10.1111","volume":"17","author":[{"given":"Bertil","family":"Friberg","sequence":"first","affiliation":[{"name":"The Br\u00e5nemark Clinic Public Dental Health Service  G\u00f6teborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten","family":"Jemt","sequence":"additional","affiliation":[{"name":"The Br\u00e5nemark Clinic Public Dental Health Service  G\u00f6teborg Sweden"},{"name":"Department Prosthetic Dentistry\/Dental Material Science Sahlgrenska Akademin University of G\u00f6teborg  G\u00f6teborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4809551"},{"key":"e_1_2_7_3_1","first-page":"515","article-title":"Sentiments expressed in relation to tooth loss: a qualitative study among edentulous Saudis","volume":"16","author":"Omar R","year":"2003","journal-title":"Int J Prosthodont"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016350701739519"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyh375"},{"key":"e_1_2_7_6_1","first-page":"7","volume-title":"Osseointegrated implants in the treatment of the edentulous jaw. 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