{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:48:41Z","timestamp":1790520521697,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:00:00Z","timestamp":1378252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      By mixing hydroxyapatite (\n                      <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\n                      ) and tricalcium phosphate (\n                      <jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content>\n                      ), biphasic calcium phosphate ceramics can be obtained, and by varying their ratio it is possible to tailor the characteristics of the biomaterial.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      The aim of the present human study was to evaluate the histological and radiographical aspects of bone formation in maxillary sinus augmentation using a 30\/70\n                      <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\n                      \u2010beta\u2010\n                      <jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content>\n                      with a reticular structure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      A total of 12 patients, undergoing two\u2010stage sinus augmentation procedure using\n                      <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\n                      \u2010beta\u2010\n                      <jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content>\n                      at a ratio of 30\/70, were included in the present study. After a 6\u2010month healing period, during implant insertion, radiographical analysis was performed, and then the bone core biopsies were harvested and processed for histology.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At radiographic evaluation, the bone gain was on average 6.85\u2009\u00b1\u20090.60\u2009mm.\n                      <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\n                      \u2010beta\u2010\n                      <jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content>\n                      30\/70 appeared to be lined by newly formed bone, with no gaps at the interface. The histomorphometric analysis revealed 26\u2009\u00b1\u20092% of residual grafted biomaterial, 29\u2009\u00b1\u20093% of newly formed bone, and 45\u2009\u00b1\u20092% of marrow spaces.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The present results indicate histologically the high biocompatibility and osteoconductivity of\n                      <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\n                      \u2010beta\u2010\n                      <jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content>\n                      30\/70, and clinically its successful use for sinus augmentation procedures.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cid.12145","type":"journal-article","created":{"date-parts":[[2013,9,5]],"date-time":"2013-09-05T00:47:02Z","timestamp":1378342022000},"page":"610-618","source":"Crossref","is-referenced-by-count":58,"title":["A Human Clinical, Histological, Histomorphometrical, and Radiographical Study on Biphasic\n                    <scp>HA<\/scp>\n                    \u2010Beta\u2010\n                    <scp>TCP<\/scp>\n                    30\/70 in Maxillary Sinus Augmentation"],"prefix":"10.1111","volume":"17","author":[{"given":"Carlo","family":"Mangano","sequence":"first","affiliation":[{"name":"Department of Morphological and Surgical Science University of Insubria Varese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna","family":"Sinjari","sequence":"additional","affiliation":[{"name":"Department of Medical, Oral and Biotechnological Sciences University of Chieti\u2010Pescara Chieti 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