{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T02:20:21Z","timestamp":1775096421634,"version":"3.50.1"},"reference-count":56,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,11,12]],"date-time":"2013-11-12T00:00:00Z","timestamp":1384214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The control of postoperative discomfort may improve the patient's quality of life as well as treatment acceptance. The aim of the present preliminary report was to assess if the use of autologous platelet concentrate during maxillary sinus augmentation may have a favorable impact on pain and other factors related to patient's quality of life in the first week after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This is an interim report of a randomized single\u2010blind study. Fifteen patients with atrophic edentulous posterior maxilla underwent maxillary sinus augmentation using deproteinized bovine bone matrix (<jats:styled-content style=\"fixed-case\">DBBM<\/jats:styled-content>) as the grafting material (control group). In other 15 patients (test group), autologous plasma rich in growth factors (<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content>) was added to <jats:styled-content style=\"fixed-case\">DBBM<\/jats:styled-content>, then a <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> clot was applied to covering the graft before suturing and finally <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> was placed over the suture in liquid form. During the first week postsurgery, all patients filled in a questionnaire for evaluation of main symptoms and daily activities. The outcomes of the questionnaires of the two groups were statistically compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the first days postsurgery, the group using <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> reported significantly less pain, swelling, and hematoma, and improved functional activities with respect to the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The adjunct of <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> to the maxillary sinus augmentation procedure produced a beneficial effect to patients' quality of life in the early postsurgical phase.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.12171","type":"journal-article","created":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T07:09:28Z","timestamp":1384326568000},"page":"708-716","source":"Crossref","is-referenced-by-count":42,"title":["Plasma Rich in Growth Factors Improves Patients' Postoperative Quality of Life in Maxillary Sinus Floor Augmentation: Preliminary Results of a Randomized Clinical Study"],"prefix":"10.1111","volume":"17","author":[{"given":"Massimo","family":"Del Fabbro","sequence":"first","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"Dental Clinic IRCCS Istituto Ortopedico Galeazzi  Milan Italy"},{"name":"Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Corbella","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences 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