{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:11:55Z","timestamp":1791389515930,"version":"4.3.3"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,1,27]],"date-time":"2015-01-27T00:00:00Z","timestamp":1422316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2016,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Vertical ridge augmentation with the use of solid bone blocks or particulate bone autograft, exposed or covered by a nonresorbable expanded polytetrafluoroethylene (\n ePTFE<\/jats:styled-content>\n ) membrane, are well known in the literature and have been shown to be effective in treating bone atrophy.\n <\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n The aim of our study was to assess the two techniques in respect to biological properties of transplanted bone in graft revascularization and bone remodeling in conjunction with dental implants.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n Ten patients were treated within the study, with a total of 12 sites with posterior mandibular edentulous ridges with insufficient bone to allow implant placement. Bone regeneration was performed using autogenous intraoral block graft or autogenous particulate graft with an\n ePTFE<\/jats:styled-content>\n barrier membrane. At 6\u201310 months, reentry surgery was performed; bone biopsies, including microscrews, were harvested; and implants were placed.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Eleven sites out of 12 healed uneventfully. A mean height gain of 5.03\u2009mm was achieved. Mean bone\u2010to\u2010implant contact and bone fill were assessed by means of histomorphometric analysis. The block specimens revealed a bone\u2010to\u2010implant contact of 42.34%, and the particulate grafts had a bone\u2010to\u2010implant contact of 26.62% (\n p<\/jats:italic>\n \u2009<\u2009.012). Bone fill values reported were 68.32% and 48.28% (\n p<\/jats:italic>\n \u2009<\u2009.019) for block specimens versus particulate grafts.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The results clearly showed that both techniques were clinically successful for subsequent implant placement and prosthetic rehabilitation. The histological outcomes, including revascularization and bone remodeling, of the two techniques differed significantly. The block grafts outperformed the particulate grafts in terms of bone\u2010to\u2010implant contact and bone fill values; however, the morbidity associated with the donor site of the block must be considered.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/cid.12267","type":"journal-article","created":{"date-parts":[[2015,1,27]],"date-time":"2015-01-27T02:31:28Z","timestamp":1422325888000},"page":"19-29","source":"Crossref","is-referenced-by-count":77,"title":["Vertical Bone Augmentation with an Autogenous Block or Particles in Combination with Guided Bone Regeneration: A Clinical and Histological Preliminary Study in Humans"],"prefix":"10.1111","volume":"18","author":[{"given":"Isabella","family":"Rocchietta","sequence":"first","affiliation":[{"name":"Department of Biomaterials Institute for Surgical Sciences Sahlgrenska Academy University of Gothenburg G\u00f6teborg Sweden"},{"name":"private practice London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Simion","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Milan Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Department of Biomaterials Institute for Surgical Sciences Sahlgrenska Academy University of Gothenburg G\u00f6teborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Trisciuoglio","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Milan Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Benigni","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Milan Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christer","family":"Dahlin","sequence":"additional","affiliation":[{"name":"Department of Biomaterials Institute for Surgical Sciences Sahlgrenska Academy University of Gothenburg G\u00f6teborg Sweden"},{"name":"Department of Oral & Maxillofacial Surgery NU Hospital Group Trollh\u00e4ttan Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060048"},{"key":"e_1_2_6_3_1","first-page":"321","article-title":"Clinical, radiographic and histologic evaluation of human periodontal defects treated with Bio\u2010Oss and Bio\u2010Gide","volume":"18","author":"Camelo M","year":"1998","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_4_1","first-page":"496","article-title":"Vertical ridge augmentation using a membrane technique associated with 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