{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:01:18Z","timestamp":1791576078044,"version":"4.3.4"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T00:00:00Z","timestamp":1455062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"DENTSPLY Implants (M\u00f6lndal, Sweden)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Purpose<\/jats:title><jats:p>Osteoporosis is a major skeletal disease affecting millions of people worldwide. Recent studies claim that patients with osteoporosis do not have a higher risk of early implant failure compared to non\u2010osteoporotic patients. The aim of this study was to assess the effect of skeletal osteoporosis and local bone density on initial dental implant stability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Seventy\u2010three patients were recruited and were assigned (based on a Dual\u2010energy X\u2010ray Absorptiometry scan) to either the osteoporosis (Opr), osteopenia (Opn), or control (C) group. Forty nine of the 73 patients received dental implants and had implant stability measured by means of resonance frequency analysis (RFA) at implant placement and at prosthetic abutment placement. On the computerized tomography scans, the cortical thickness and the bone density (Hounsfield Units) at the sites of implant placement were measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At implant placement, primary stability was on average lower in group Opr (63.3\u2009\u00b1\u200910.3 ISQ) than in group Opn (65.3\u2009\u00b1\u20097.5 implant stability qutient (ISQ)), and group C (66.7\u2009\u00b1\u20098.7 ISQ). At abutment placement, a similar trend was observed: group Opr (66.4\u2009\u00b1\u20099.5 ISQ) scored lower than group Opn (70.7\u2009\u00b1\u20097.8 ISQ), while the highest average was for group C (72.2\u2009\u00b1\u20097.2 ISQ). The difference between groups Opr and C was significant. Implant length and diameter did not have a significant effect on implant stability as measured with RFA. A significant correlation was found between local bone density and implant stability for all regions of interest.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Implant stability seems to be influenced by both local and skeletal bone densities. The lower stability scores in patient with skeletal osteoporosis reinforce the recommendations that safe protocols and longer healing times could be recommended when treating those patients with dental implants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.12290","type":"journal-article","created":{"date-parts":[[2016,2,11]],"date-time":"2016-02-11T21:26:20Z","timestamp":1455225980000},"page":"253-260","source":"Crossref","is-referenced-by-count":72,"title":["Influence of Skeletal and Local Bone Density on Dental Implant Stability in Patients with Osteoporosis"],"prefix":"10.1111","volume":"18","author":[{"given":"Joe","family":"Merheb","sequence":"first","affiliation":[{"name":"Unit of Periodontology, Department of Oral Health Sciences University of Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy","family":"Temmerman","sequence":"additional","affiliation":[{"name":"Unit of Periodontology, Department of Oral Health Sciences University of Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Rasmusson","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery The Sahlgrenska Academy, University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"K\u00fcbler","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Plastic Surgery University of Wuerzburg Wuerzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Thor","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Institute of Surgical Sciences, Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Quirynen","sequence":"additional","affiliation":[{"name":"Unit of Periodontology, Department of Oral Health Sciences University of Leuven Leuven Belgium"},{"name":"Research Group Periodontology &amp; Oral microbiology, Department of Oral Health Sciences, University of Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01622200"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001980200069"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01188.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-13-00211"},{"key":"e_1_2_6_6_1","first-page":"199","volume-title":"Proceedings of the Clinical Dentistry","author":"Lekholm U","year":"1985"},{"key":"e_1_2_6_7_1","first-page":"905","article-title":"Effect of osteoporotic status on the survival of titanium dental implants","volume":"23","author":"Holahan CM","year":"2008","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-849X.2008.00433.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12228"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2005.tb00076.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1563\/1548-1336(2004)30<162:APVFII>2.0.CO;2"},{"key":"e_1_2_6_12_1","first-page":"10","article-title":"Two alternative surgical techniques for enhancing primary implant stability in the posterior maxilla: a clinical study including bone density, insertion torque, and resonance frequency analysis data. 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