{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:01:32Z","timestamp":1790262092635,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,2,28]],"date-time":"2016-02-28T00:00:00Z","timestamp":1456617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate (clinically, histologically, and histo\u2010morphometrically) the use of composite materials (Biphasic calcium sulphate [BCS] with \u03b2 Tri\u2010Calcium Phosphate (\u03b2\u2010TCP) and Hydroxyapatite [HA]) in extraction socket sites and compare it to un\u2010disturbed natural healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>Prospective clinical trial of 36 patients (40 extraction sockets) were randomly assigned to either test or control group. Alveolar ridge horizontal dimension was measured in the middle of the socket at crest and 3 and 6 mm subcrestally. Crestal vertical height was measured at baseline surgery and at 4 month re\u2010entry, at which time bone core biopsies were harvested from the center of the edentulous ridge. Histo\u2010morphometric evaluation of the samples was performed using hematoxylin &amp; eosin stains and morphometric software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The change in horizontal ridge width was higher in the control compared to the experimental group: 2.28\u2009\u00b1\u20092.36 mm versus 0.03\u2009\u00b1\u20092.32 mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.007) at \u22123 mm and 2.28\u2009\u00b1\u20092.43 versus 0.035\u2009\u00b1\u20093.05 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.02) at \u22126 mm, for the experimental and control sites, respectively. The vertical distance form bone crest to neighboring horizontal line interconnecting the neighboring teeth was minimal in both groups (0.307\u2009\u00b1\u20092.01 mm versus 0.14\u2009\u00b1\u20092.03 mm [\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.41]). Residual scaffolds occupied 15.99\u2009\u00b1\u200911.4% of the volume in the grafted (test) sites while bone area fraction was not statistically different among the groups (47.7\u2009\u00b1\u200910.6% versus 52.6\u2009\u00b1\u200911.6%, test versus control, respectively\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.39). The percentage of connective tissue in the control group was significantly higher that test group (36.3\u2009\u00b1\u200919.4% versus 46.7\u2009\u00b1\u200910.6% test versus control, respectively,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.013).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Ridge preservation technique using a combination of two synthetic bone grafts \u03b2\u2010TCP and HA with BCS resulted in greater stability in the horizontal dimension after 4 months.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cid.12415","type":"journal-article","created":{"date-parts":[[2016,2,28]],"date-time":"2016-02-28T18:18:58Z","timestamp":1456683538000},"page":"1163-1170","source":"Crossref","is-referenced-by-count":43,"title":["Ridge Preservation Using Composite Alloplastic Materials: A Randomized Control Clinical and Histological Study in Humans"],"prefix":"10.1111","volume":"18","author":[{"given":"Yaniv","family":"Mayer","sequence":"first","affiliation":[{"name":"Doctor, School of Graduate Dentistry, Department of Periodontics, Rambam Health Care Campus  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadar","family":"Zigdon\u2010Giladi","sequence":"additional","affiliation":[{"name":"Associate Professor, Head of Lab of Bone Regeneration, School of Graduate Dentistry, Department of Periodontics, Rambam Health Care Campus  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli E.","family":"Machtei","sequence":"additional","affiliation":[{"name":"Professor, Head of the School of Graduate Dentistry, Department of Periodontics, Rambam Health Care Campus  Haifa 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