{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:52:39Z","timestamp":1790236359330,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T00:00:00Z","timestamp":1605139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005847","name":"Health and Medical Research Fund","doi-asserted-by":"publisher","award":["05161626"],"award-info":[{"award-number":["05161626"]}],"id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Conventional freehand immediate placement of dental implants is technically challenging in the jaw reconstructive surgery. Computer\u2010aided surgery might be the best solution, however, there has not been any standard approach to ensure the accuracy and efficiency of simultaneous dental implants in fibula flap jaw reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>We aim to evaluate the clinical outcome of simultaneous dental implant in fibula flap using the \u201cthree\u2010in\u2010one\u201d patient\u2010specific surgical guide (3\u2010in\u20101\u2010PSSG) in an open\u2010label, prospective, single\u2010arm, and single\u2010center clinical trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A novel computer\u2010aided designed and three\u2010dimensional (3D) printed 3\u2010in\u20101\u2010PSSG, which contains functions of fibula segmentation, surgical plate positioning and implant placement, was used to facilitate the reconstructive surgery and simultaneous dental implant placement. The intraoperative success of dental implant placement, implant survival rate and accuracy of dental implant placement were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From November 2018 to June 2020, 15 consecutive patients with 48 dental implants were enrolled in this study. Fifteen 3\u2010in\u20101\u2010PSSGs were fabricated with a mean number of dental implants per guide of 3.2 \u00b1\u20091.5. The intraoperative success rate of this approach was 14 out of 15. With an average follow\u2010up period of 40\u2009weeks, the overall implant survival rate was 83.3% (40\/48). Eight implants were removed due to two fibula flap failures. The mean deviation at the implant platform and implant apex were 2.8\u2009mm (interquartile range [IQR]: 1.9\u20103.4) and 3.2\u2009mm (IQR: 2.0\u20104.6), and the angular deviation was 2.5\u00b0 (IQR: 1.1\u20106.8).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our preliminary data indicated that the 3D printed 3\u2010in\u20101\u2010PSSG facilitated simultaneous dental implant in fibula flap jaw reconstruction with a favorable intraoperative success and short\u2010term clinical outcome. It might be a viable alternative to allow one\u2010step immediate oral rehabilitation in patients underwent jaw reconstruction with free flaps. Long\u2010term results with a larger sample size are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.12954","type":"journal-article","created":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T18:57:36Z","timestamp":1605207456000},"page":"43-53","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["\u201cThree\u2010in\u2010one\u201d patient\u2010specific surgical guides for simultaneous dental implants in fibula flap jaw reconstruction: A prospective case series"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4422-5258","authenticated-orcid":false,"given":"Wang\u2010yong","family":"Zhu","sequence":"first","affiliation":[{"name":"Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry The University of Hong Kong  Pok Fu Lam Hong Kong Special Administrative 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