{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:08:49Z","timestamp":1790885329271,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T00:00:00Z","timestamp":1647820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In a number of previous studies, patients with reported penicillin allergies have been documented to experience higher rates of dental implant failure than those who had not reported this allergy. The authors of this study aimed to determine whether an increased risk of implant failure is associated with patient\u2010reported penicillin allergy and which antibiotic was administered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Materials<\/jats:title><jats:p>A retrospective study was conducted through chart review of patients who received dental implants at the New York University College of Dentistry. Participants were eligible if they received one or more dental implants at the College and provided at least 1 year of follow\u2010up data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall implant failure rate was 12.9%. The failure rate in patients who reported no allergy to penicillin and took amoxicillin was 8.4%, while the failure rate in the allergy\u2010reporting group was 17.1% (adjusted OR\u00a0=\u00a02.22, 95% CI\u00a0=\u00a01.44\u20133.44). The failure rate in allergy\u2010reporting patients who took Clindamycin was also higher than in those who took amoxicillin (19.9%; adjusted OR\u00a0=\u00a02.9, 95% CI\u00a0=\u00a01.77\u20134.47) or any antibiotic other than amoxicillin (20.9%; adjusted OR\u00a0=\u00a02.77, 95% CI\u00a0= 1.77\u20134.32).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Significant findings included a lower implant failure rate in patients taking amoxicillin than in patients taking other antibiotics. There was a significant increase in early implant failure in allergy reporting patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13082","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T17:06:08Z","timestamp":1647882368000},"page":"301-306","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Dental implant failure rates in patients with self\u2010reported allergy to penicillin"],"prefix":"10.1111","volume":"24","author":[{"given":"Bagheri","family":"Zahra","sequence":"first","affiliation":[{"name":"Ashman Department of Periodontology and Implant Dentistry PI New York University College of Dentistry  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barrese","family":"Nicholas","sequence":"additional","affiliation":[{"name":"Ashman Department of Periodontology and Implant Dentistry New York University College of Dentistry  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubinshtein","family":"Geoffrey","sequence":"additional","affiliation":[{"name":"Ashman Department of Periodontology and Implant Dentistry New York University College of Dentistry  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahedi","family":"Dina","sequence":"additional","affiliation":[{"name":"Ashman Department of Periodontology and Implant Dentistry New York University College of Dentistry  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malvin N.","family":"Janal","sequence":"additional","affiliation":[{"name":"Epidemiology and Health Promotion New York University College of Dentistry  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Froum","family":"Stuart","sequence":"additional","affiliation":[{"name":"Ashman Department of Periodontology and Implant Dentistry New York University College of 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