{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:58:56Z","timestamp":1791248336928,"version":"4.1.0"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T00:00:00Z","timestamp":1657411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The present randomized controlled trial compares for the first time the vestibular socket therapy (VST) to the contour augmentation technique in the management of compromised fresh extraction sockets in the maxillary esthetic zone, regarding mid\u2010facial soft tissue changes (primary outcome), mesial and distal papillae dimensions, horizontal soft tissue changes and labial bone plate thickness at apical, middle and coronal levels (secondary outcomes) over 1\u2010year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Forty participants with single nonrestorable maxillary teeth in the esthetic zone were randomized into two groups; VST (test; <jats:italic>n<\/jats:italic>\u00a0=\u200920) utilizing vestibular access for guided bone regeneration (GBR) with immediate implant placement, or contour augmentation (control; <jats:italic>n<\/jats:italic>\u00a0=\u200920) undergoing an initial healing period followed by implant placement with GBR through a conventional access flap.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All implants were successfully osseo\u2010integrated, except for one implant in the test group. VST showed significantly less mid\u2010facial soft tissue changes of \u22120.53\u2009\u00b1\u20091.17\u2009mm versus \u22121.87\u2009\u00b1\u20090.69\u2009mm in the control group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001). Similarly, changes in mesial papilla (test\u00a0=\u00a0\u22120.64\u2009\u00b1\u20090.95\u2009mm, control\u00a0=\u00a0\u22121.20\u2009\u00b1\u20090.81\u2009mm), distal papilla (test\u00a0=\u00a0\u22120.56\u2009\u00b1\u20091.17\u2009mm, control\u00a0=\u00a0\u22121.26\u2009\u00b1\u20090.63\u2009mm), horizontal soft\u2010tissue (test\u00a0=\u00a0\u22120.82\u2009\u00b1\u20090.95\u2009mm, control\u00a0=\u00a0\u22121.84\u2009\u00b1\u20090.88\u2009mm; <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.05) were significantly less in VST. Intra\u2010group comparisons demonstrated a significant increase in labial bone thickness, with no differences between groups. Regression analysis revealed a significant correlation between VST as well as increased coronal bone thickness with the reduction in mid\u2010facial soft\u2010tissue changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The VST showed less soft\u2010tissue changes and could represent an innovative technique for implant placement in the maxillary esthetic zone. Both techniques showed a high implant survival rate and increased bone thickness after 12\u2009months.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13120","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T00:29:41Z","timestamp":1657499381000},"page":"559-568","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Immediate implant placement utilizing vestibular socket therapy versus early implant placement with contour augmentation for rehabilitation of compromised extraction sockets in the esthetic zone: A randomized controlled clinical trial"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7384-8350","authenticated-orcid":false,"given":"Abdelsalam","family":"ElAskary","sequence":"first","affiliation":[{"name":"Elaskary and Associates Educational Center and Institute for Dental Implants  Alexandria Egypt"},{"name":"College of Dentistry University of New York  New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8853-7253","authenticated-orcid":false,"given":"Ahmed","family":"Elfana","sequence":"additional","affiliation":[{"name":"Oral Medicine and Periodontology Department, Faculty of Dentistry Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moatez","family":"Meabed","sequence":"additional","affiliation":[{"name":"Periodontist, Private Practice  Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9639-1189","authenticated-orcid":false,"given":"Iman","family":"Abd\u2010ElWahab Radi","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Faculty of Dentistry Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Akram","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery Department, Faculty of Dentistry Alexandria University  Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Fawzy El\u2010Sayed","sequence":"additional","affiliation":[{"name":"Oral Medicine and Periodontology Department, Faculty of Dentistry Cairo University  Cairo Egypt"},{"name":"Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine Christian Albrechts University  Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12170"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12709"},{"issue":"4","key":"e_1_2_11_4_1","first-page":"313","article-title":"Bone healing and soft tissue contour changes following single\u2010tooth extraction: a clinical and radiographic 12\u2010month prospective 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