{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:32:04Z","timestamp":1791379924097,"version":"4.3.3"},"reference-count":46,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T00:00:00Z","timestamp":1664928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>to retrospectively evaluate clinical and radiographic outcomes of immediate, flapless full\u2010arch prostheses, supported by 4\/6 implants according to prosthetic\u2010driven planning and guided surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The study involved 28 edentulous patients (20 female\/8 males; average age 67.75\u2009\u00b1\u20098.627\u2009years), 32 prostheses (17 all\u2010on\u20104\/15 all\u2010on\u20106) and 164 implants. The Implants survival, prostheses success\/survival, peri\u2010implant marginal bone loss, incidence of biological and prosthetic complications were evaluated. Multiple linear regression analysis was performed to analyze the influence of implant and patient characteristics on marginal bone loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cumulative implant survival rate was 89.7% for all\u2010on\u2010four (seven failures) and 99.0% for all\u2010on\u2010six (one failure) after a mean follow\u2010up of 6.46\u2009\u00b1\u20092.236\u2009years (range 1\u201310\u2009years). Cumulative prosthesis success rate was 51.5% (58.8% for all\u2010on\u2010four\/ 43.8% for all\u2010on\u2010six). Prosthesis survival rate was 88.2% for all\u2010on\u2010four. No failure was registered in all\u2010on\u2010six. Mean value of marginal bone loss was 1.38\u2009\u00b1\u20090.1.28\u2009mm at 5\u2010year and 2.09\u2009\u00b1\u20090.56\u2009mm at 10\u2010year follow\u2010up. No difference was found in the mean value of marginal bone resorption between all\u2010on\u2010four (1.56\u2009\u00b1\u20091.61\u2009mm) and all\u2010on\u2010six (1.20\u2009\u00b1\u20090.85\u2009mm) (<jats:italic>p<\/jats:italic>\u00a0=\u20090.104) and between tilted (1.22\u2009\u00b1\u20091.29\u2009mm) and axial implants (1.44\u2009\u00b1\u20091.27\u2009mm) (<jats:italic>p<\/jats:italic>\u00a0=\u20090.385) after 5\u2010year follow\u2010up. The incidence of biological complications was 1.0% in all\u2010on\u2010six (one mucositis) and 10.3% in all\u2010on\u2010four (two peri\u2010implantitis). Prosthetic complications affected teeth of final rehabilitations with 3 detachments, 10 chippings or fractures, and 3 severe occlusal wears.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Based on the results and within the limitations of the present study, the implant\u2010supported hybrid prosthesis according to prosthetic\u2010driven planning and guided surgery showed to be an efficient, safe, and effective approach to rehabilitate edentulous jaws.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13134","type":"journal-article","created":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T12:19:58Z","timestamp":1664972398000},"page":"831-844","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Immediate flapless full\u2010arch rehabilitation of edentulous jaws on 4 or 6 implants according to the prosthetic\u2010driven planning and guided implant surgery: A retrospective study on clinical and radiographic outcomes up to 10\u2009years of follow\u2010up"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6537-7050","authenticated-orcid":false,"given":"Gerardo","family":"La Monaca","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Sciences, Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4095-0900","authenticated-orcid":false,"given":"Nicola","family":"Pranno","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Sciences, Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6631-7444","authenticated-orcid":false,"given":"Susanna","family":"Annibali","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Sciences, Sapienza University of Rome  Rome 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