{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:42:56Z","timestamp":1790631776457,"version":"4.1.0"},"reference-count":74,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study analyzes early marginal bone modifications occurring around platform\u2010switched implants with conical connection placed 1 or 2\u2009mm subcrestally.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This crossover randomized controlled trial enrolled partially edentulous patients needing two implants in either the posterior maxilla or mandible. Each patient received two platform\u2010switched implants with conical connection inserted 2\u2009mm (Test) and 1\u2009mm (Control) subcrestally. Definitive abutments were immediately connected and, after 4\u00a0months of unsubmerged healing, screwed metal\u2010ceramic crowns were delivered. Radiographs were taken at implant placement (T0), prosthesis delivery (T1), and after 1\u2009year of prosthetic loading (T2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010one patients (25 males and 26 females; mean age 61.2\u2009\u00b1\u200912.1\u2009years) totaling 102 implants were included in the final analysis. Mean peri\u2010implant bone level (PBL) reduction from T0 to T2 was not significantly different around Test (0.49\u2009\u00b1\u20090.32\u2009mm) and Control implants (0.46\u2009\u00b1\u20090.35\u2009mm;<jats:italic>p<\/jats:italic>\u00a0=\u00a00.66). Multivariate linear regression models highlighted a significant positive correlation between history of periodontitis and PBL reduction. At T2, no Test group implant and 6 Control group implants exhibited PBL below the implant platform (11.8% of Control group implants).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No significant differences in peri\u2010implant marginal bone changes were demonstrated after 1\u2009year of prosthetic loading between platform\u2010switched implants with conical connection inserted either 1 or 2\u2009mm subcrestally. However, 2\u2009mm subcrestal placement resulted in deeper implant positioning at T2, with no exposure of treated implant surface and potential preventive effect against subsequent peri\u2010implant pathology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13186","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T01:34:19Z","timestamp":1675301659000},"page":"398-408","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Marginal bone changes around platform\u2010switched conical connection implants placed 1 or 2\u2009mm subcrestally: A multicenter crossover randomized controlled trial"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4017-4980","authenticated-orcid":false,"given":"Claudio","family":"Stacchi","sequence":"first","affiliation":[{"name":"Department of Medical, Surgical and Health Sciences University of Trieste Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4395-116X","authenticated-orcid":false,"given":"Luca","family":"Lamazza","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Sciences Sapienza University of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9767-4401","authenticated-orcid":false,"given":"Antonio","family":"Rapani","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical and Health Sciences University of Trieste Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5647-4414","authenticated-orcid":false,"given":"Giuseppe","family":"Troiano","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Messina","sequence":"additional","affiliation":[{"name":"Private Practice Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Antonelli","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Magna Gr\u00e6cia University Catanzaro Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5091-6979","authenticated-orcid":false,"given":"Amerigo","family":"Giudice","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Magna Gr\u00e6cia University Catanzaro Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Lombardi","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Magna Gr\u00e6cia University Catanzaro Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.2000.5.1.119"},{"issue":"2","key":"e_1_2_10_3_1","first-page":"113","article-title":"Influence of 3\u2010D bone\u2010to\u2010implant relationship on esthetics","volume":"25","author":"Grunder U","year":"2005","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01388.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12176"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13537"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.9.1412"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2000.011001001.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13128"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1992.030301.x"},{"issue":"4","key":"e_1_2_10_11_1","first-page":"527","article-title":"Microbial leakage and marginal fit of the implant\u2010abutment interface","volume":"12","author":"Jansen VK","year":"1997","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.3.346"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2017.08.025"},{"issue":"2","key":"e_1_2_10_14_1","first-page":"35","article-title":"One abutment one time vs. repeatable abutment disconnections in implants, restored with cemented \/ screw retained fixed partial dentures: marginal bone level changes. A systematic review and meta\u2010analysis","volume":"23","author":"Vat\u0117nas I","year":"2021","journal-title":"Stomatologija"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513519800"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13108"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13450"},{"issue":"3","key":"e_1_2_10_18_1","first-page":"279","article-title":"Influence of abutment height and vertical mucosal thickness on early marginal bone loss around implants. A randomized clinical trial with an 18\u2010month post\u2010loading clinical and radiographic evaluation","volume":"13","author":"Spinato S","year":"2020","journal-title":"Int J Oral Implantol (Berl)"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.9523"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2017.07.022"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.3.322"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(81)80077-4"},{"issue":"1","key":"e_1_2_10_23_1","first-page":"11","article-title":"The long\u2010term efficacy of currently used dental implants: a review and proposed criteria of success","volume":"1","author":"Albrektsson T","year":"1986","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(89)90081-4"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12324"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515608832"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12535"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12612"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13000"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13122"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12903"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12871"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9103320"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090317"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.4017"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3184"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8081168"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20747"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12990"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.6509"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2301-1"},{"key":"e_1_2_10_42_1","first-page":"3","volume-title":"Partial denture construction","author":"Kennedy E","year":"1928"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.id.0000247855.75691.03"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2015.08.005"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40729-016-0048-0"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12222"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13766"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13956"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12127"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12337"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12620"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090115"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-019-0809-2"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3411"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13129"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.8425"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18084284"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107BOR-2014.vol28.0023"},{"issue":"5","key":"e_1_2_10_59_1","doi-asserted-by":"crossref","first-page":"660","DOI":"10.4103\/njcp.njcp_362_20","article-title":"Evaluating the effect of subcrestal placement on platform switched short dental implants and von mises stress in D3 bone\u2010a 3D FEM study","volume":"24","author":"Reddy MS","year":"2021","journal-title":"Niger J Clin Pract"},{"issue":"4","key":"e_1_2_10_60_1","article-title":"Biomechanical evaluation of stress distribution in equicrestal and sub\u2010crestally placed, platform\u2010switched Morse taper dental implants in D3 bone: finite element analysis","volume":"14","author":"Ellendula Y","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2002.17.1.77"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2012.08.005"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2009.09.010"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12398"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.36060"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12829"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.594"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11072014"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13954"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2017.160802"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13077"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13066"},{"key":"e_1_2_10_73_1","first-page":"39","article-title":"History of treated periodontitis and smoking as risks for implant therapy","volume":"24","author":"Heitz\u2010Mayfield LJA","year":"2009","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.4245"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma12152398"}],"container-title":["Clinical Implant Dentistry and Related Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cid.13186","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cid.13186","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cid.13186","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T01:36:31Z","timestamp":1701826591000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cid.13186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":74,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/cid.13186"],"URL":"https:\/\/doi.org\/10.1111\/cid.13186","archive":["Portico"],"relation":{},"ISSN":["1523-0899","1708-8208"],"issn-type":[{"value":"1523-0899","type":"print"},{"value":"1708-8208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"2022-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}