{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:37:46Z","timestamp":1787769466671,"version":"build-2784847793"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Different biomaterials were suggested for sinus floor augmentation (SFA). Recently, new materials were launched showing true bone formation without remnants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this prospective study was to evaluate an hydroxyapatite\u2010based, sugar cross\u2010linked collagen sponge (OSSIX\u2122 Bone) in transcrestal SFA (t\u2010SFA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Twenty\u2010four patients with edentulous posterior maxilla and residual bone height (RBH) &gt;4\u2009mm underwent t\u2010SFA with OSSIX\u2122 Bone as grafting material and simultaneous implant placement. The implant Stability Quotient (ISQ) was measured by resonance frequency analysis (RFA) directly after implant insertion and at 6\u2009months. Differences in bone height (BH) and volume were determined in CBCT and x\u2010rays at baseline versus 1\u2009year of follow\u2010up. Graft volume was evaluated by tridimensional reconstructions. Linear regression analysis was used to evaluate the effect of bucco\u2010palatal sinus dimension, RBH, and length of the implant protruding (PIL) into the sinus, on the graft height (GH) changes up to 1\u2009year, and on the graft volume at 1\u2009year. Autocorrelation between time lag and augmented bone volume was evaluated through time series analysis correlograms. Health\u2010related quality\u2010of\u2010life outcomes were captured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010two patients completed the study. The mean RBH measured at baseline was 5.81\u2009\u00b1\u20092.2\u2009mm. The mean graft volume was 1085.8\u2009\u00b1\u2009733.4\u2009mm<jats:sup>3<\/jats:sup>. The mean GH, measured in the immediate post\u2010operative period, at 6 and 12\u2009months respectively, was 7.24\u2009mm \u00b11.94; 6.57\u2009mm\u2009\u00b1\u20092.30; 5.46\u2009mm\u2009\u00b1\u20092.04. The mean ISQ measured after the implant placement was 62.19\u2009\u00b1\u20098.09, and 6\u2009months later was 76.91\u2009\u00b1\u20094.50. There was a significant correlation between buccolingual dimension and graft volume at 1\u2009year. Neither buccolingual volume nor RBH had a significant effect on GH change, while the PIL showed a significant positive correlation (P\u2009=\u20090.02 and P\u2009=\u20090.03 at 6 and 12\u2009months, respectively). The correlograms indicated no significant correlation, meaning that there is no tendency for graft volume to increase or decrease over time, therefore suggesting graft stability, at least up to one year of follow\u2010up. 86% of patients had no chewing interference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Within the limitations of the study, OSSIX\u2122 Bone could be considered a valid material for SFA due to its manageability and its positive results in promoting new bone formation with long\u2010term stability. T\u2010SFA is confirmed as a less invasive and less painful method.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13236","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T10:30:19Z","timestamp":1686220219000},"page":"974-983","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Sinus floor augmentation using crestal approach in conjunction with hydroxyapatite\/cross\u2010linked collagen sponge: A pilot study"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9875-2929","authenticated-orcid":false,"given":"Luigi","family":"Canullo","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences University of Genova  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7144-0984","authenticated-orcid":false,"given":"Massimo","family":"Del Fabbro","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical, and Dental Sciences University of Milan  Milan Italy"},{"name":"Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Colantonio","sequence":"additional","affiliation":[{"name":"Private Practice  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Iacono","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Science Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Raffone","sequence":"additional","affiliation":[{"name":"Private Practice  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Pedetta","sequence":"additional","affiliation":[{"name":"Private Practice  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahnawaz","family":"Khijmatgar","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical, and Dental Sciences University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lior","family":"Shapira","sequence":"additional","affiliation":[{"name":"Department of Periodontology Hebrew University and Hadassah Medical Center  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2012.03.016"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12615"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2015.07.007"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2008.01263.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2011.10.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12286"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12758"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12464"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12985"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708\u20108208.2011.00399.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0000000000000798"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2008.01661.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.08.009"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2016.09.023"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12210"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2007.01424.x"},{"issue":"7","key":"e_1_2_10_18_1","first-page":"454","article-title":"Evolution of biomaterials in implant dentistry leads to enhanced tissue quality","volume":"43","author":"Neiva R","year":"2022","journal-title":"Compend Contin Educ Dent"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_2_10_20_1","unstructured":"Dhand NK KhatkarMS. 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