{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:00:46Z","timestamp":1790262046636,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005667","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e Inova\u00e7\u00e3o do Estado de Santa Catarina","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005667","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The present systematic review aimed to identify and summarize the clinical, radiographic, and histological outcomes of alveolar ridge preservation using bone xenografts and absorbable sealing materials compared with spontaneous healing in the esthetic zone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Randomized clinical trials (RCTs) fulfilling specific eligibility criteria were included. Two review authors independently searched for eligible studies, extracted data from the published reports and performed the risk of bias assessment (RoB 2 tool). Study results were summarized using random effects meta\u2010analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirteen articles concerning 10 RCTs were included, involving a total of 357 participants. Most of studies were considered as \u201clow\u201d risk of bias. Meta\u2010analyses indicated less horizontal (difference in means\u2014MD\u2009=\u20091.88\u2009mm; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), vertical mid\u2010buccal (MD\u2009=\u20091.84\u2009mm; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and vertical mid\u2010lingual (MD\u2009=\u20092.27\u2009mm; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) bone resorption in alveolar ridge preservation compared to spontaneous healing as assessed clinically. Bone changes assessed radiographically showed consistent results in terms of horizontal (at 1\u2009mm: MD\u2009=\u20091.84\u2009mm, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), vertical mid\u2010buccal (MD\u2009=\u20090.95\u2009mm; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and mid\u2010lingual (MD\u2009=\u20090.62\u2009mm; <jats:italic>p<\/jats:italic>\u2009=\u20090.05) resorption. Part of the bone resorption in the spontaneous healing group was compensated by soft\u2010tissues, since the observed differences between groups in linear ridge reduction evaluated through cast models superimposition were smaller (MD\u2009=\u20090.52\u2009mm; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Alveolar ridge preservation with xenogeneic bone substitutes and non\u2010autogenous resorbable socket sealing materials is efficacious in reducing post\u2010extraction bone and ridge changes in the esthetic region.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13257","type":"journal-article","created":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T05:28:36Z","timestamp":1694064516000},"page":"4-14","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Efficacy of alveolar ridge preservation with xenografts and resorbable socket sealing materials in the esthetic region: A systematic review with meta\u2010analyses"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0611-1839","authenticated-orcid":false,"given":"Karin","family":"Apaza\u2010Bedoya","sequence":"first","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0724-0560","authenticated-orcid":false,"given":"Gabriel Leonardo","family":"Magrin","sequence":"additional","affiliation":[{"name":"Centre for Education and Research on Dental Implants (CEPID), Department of Dentistry Federal University of Santa Catarina (UFSC)  Florian\u00f3polis Brazil"},{"name":"Department of Surgery and Medical\u2010Surgical Specialties (Dentistry \u2010 Unit of Periodontology), Faculty of Medicine and Odontology University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5646-083X","authenticated-orcid":false,"given":"Mario","family":"Romandini","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Faculty of Dentistry University of Oslo  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9251-513X","authenticated-orcid":false,"given":"Juan","family":"Blanco\u2010Carri\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Surgery and Medical\u2010Surgical Specialties (Dentistry \u2010 Unit of Periodontology), Faculty of Medicine and Odontology University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4209-0054","authenticated-orcid":false,"given":"Cesar Augusto 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