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Clinical studies and in vitro studies reporting the accuracy of digital full arch impressions were included. The primary outcome is the 3\u2010dimensional deviations between the study reference models. A risk of bias assessment was performed for clinical studies. A stratified meta\u2010analysis and a single\u2010armed meta\u2010analysis were conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 49 studies were included, with 8 clinical studies and 41 in vitro studies. For comparison between IOS and conventional impressions, studies were categorized into two groups based on the different measurement methods employed: RMS and CMM. In studies using RMS, the result favored the IOS in the unparalleled situation with the mean difference of \u221299.29\u2009\u03bcm (95% CI: [\u2212141.38, \u221257.19], <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200981%), while the result was opposite with the mean difference of 13.62\u2009\u03bcm (95% CI: [10.97, 16.28], <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200926%) when implants were paralleled. For different brands of IOS, the accuracy ranged from 76.11\u2009\u03bcm (95% CI: [42.36, 109.86]) to 158.63\u2009\u03bcm (95% CI: [\u221214.68, 331.93]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Accuracy of intraoral scan is clinically acceptable in edentulous arches, especially for unparalleled implants. More clinical studies are needed to verify the present finding.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13321","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T14:09:01Z","timestamp":1711116541000},"page":"847-861","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Does intra\u2010oral scan improve the impression accuracy of full\u2010arch implant\u2010supported prostheses: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"26","author":[{"given":"Zheng\u2010zhen","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Implant Dentistry, Shanghai Ninth People's Hospital College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology &amp; Shanghai Research Institute of Stomatology  Shanghai 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Shanghai Key Laboratory of Stomatology &amp; Shanghai Research Institute of Stomatology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010Yu","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry, Shanghai Ninth People's Hospital College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology &amp; Shanghai Research Institute of Stomatology  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2022.104335"},{"issue":"11","key":"e_1_2_10_3_1","first-page":"343","article-title":"Laser in contemporary dentistry","volume":"85","author":"G\u00e1sp\u00e1r L","year":"1992","journal-title":"Fogorv 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