{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:39:31Z","timestamp":1791038371394,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to compare implant stabilities between the immediate and early loaded, immediately placed bone\u2010level tapered dental implants in the maxilla and to evaluate marginal bone loss (MBL), oral health\u2010related quality of life (OHRQoL), and patient satisfaction at a 2\u2010year follow\u2010up. A pilot, prospective, randomized, controlled clinical trial was conducted on 24 maxillary failing dentition patients. The bone\u2010level tapered implants of 12 patients were immediately loaded with temporary restorations, while the other 12 patients did not receive any kind of temporization. Implant\u2010supported screw\u2010retained complete porcelain\u2010fused\u2010to\u2010metal prostheses were delivered to all patients in the seventh postoperative week. The insertion torque values of implants assigned to the immediate and early loading groups were 33.0\u2009\u00b1\u20094.87 and 29.26\u2009\u00b1\u20098.31 Ncm, respectively. The dynamics of implant stability changes from implant placement up to a 2\u2010year follow\u2010up were similar for both groups (Penguin\u00ae, <jats:italic>p<\/jats:italic>\u2009=\u20090.268; Ostell\u00ae, <jats:italic>p<\/jats:italic>\u2009=\u20090.552), while the MBL was at submillimeter level. The cumulative implant survival rate was 91.80% for immediately loaded implants and 97.22% for early loaded implants, without significant difference (<jats:italic>p<\/jats:italic>\u2009=\u20090.162). The total score on the Oral Health Impact Profile questionnaire significantly decreased over time in both groups, indicating improvement in OHRQoL (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and the high level of patient satisfaction remained after 2\u2009years of function regardless of a loading protocol. Both loading protocols, immediate and early, of six immediately placed bone\u2010level tapered dental implants are an adequate treatment choice for fixed rehabilitation of the maxillary failing dentition.<\/jats:p>","DOI":"10.1111\/cid.13334","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T06:28:50Z","timestamp":1714631330000},"page":"688-703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Immediate versus early loading of immediately placed bone\u2010level tapered dental implants with hydrophilic surface in full arch maxillary rehabilitation: A pilot randomized clinical trial with 2\u2010year follow\u2010up"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7939-0974","authenticated-orcid":false,"given":"Aleksa","family":"Markovi\u0107","sequence":"first","affiliation":[{"name":"Implant Center, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Todorovi\u0107","sequence":"additional","affiliation":[{"name":"Implant Center, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirko","family":"Gli\u0161i\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Prosthodontics, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jovana","family":"Markovi\u0107","sequence":"additional","affiliation":[{"name":"Implant Center, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7064-0922","authenticated-orcid":false,"given":"Branislav","family":"Ili\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Oral surgery School of Dental Medicine, University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bojan","family":"Janji\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Oral surgery School of Dental Medicine, University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tijana","family":"Mi\u0161i\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Oral surgery School of Dental Medicine, University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Branka","family":"Trifkovi\u0107","sequence":"additional","affiliation":[{"name":"Implant Center, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uro\u0161","family":"Vu\u010di\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Oral surgery School of Dental Medicine, University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miodrag","family":"\u0160\u0107epanovi\u0107","sequence":"additional","affiliation":[{"name":"Implant Center, School of Dental Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel M.","family":"Dard","sequence":"additional","affiliation":[{"name":"Columbia University College of Dental Medicine  New York New York USA"},{"name":"Institut Straumann  Basel 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