{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T15:22:53Z","timestamp":1773847373105,"version":"3.50.1"},"reference-count":62,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T00:00:00Z","timestamp":1722211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001098"],"award-info":[{"award-number":["82001098"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008233","name":"School of Medicine, Shanghai Jiao Tong University","doi-asserted-by":"publisher","award":["JYJC202004"],"award-info":[{"award-number":["JYJC202004"]}],"id":[{"id":"10.13039\/501100008233","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>This study aimed to systematically compare the patients undergoing lateral MSFA therapies utilizing bovine\u2010originated xenografts versus varied synthetic bone grafting materials.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pubmed, Scopus, Embase, and Cochrane Library were searched up to April 2023, compensated by a manual search in selected journals. Studies reporting histological outcomes (residual bone graft, newly formed bone, non\u2010mineralized tissue) and clinical outcomes (implant survival, ISQ value) were included. Several analyses were performed, including meta\u2010analysis, sensitivity study, and Egger's regression tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixteen clinical\/randomized control trials were included in this systematic review, among which 12 were enrolled in a meta\u2010analysis. The percentage of newly formed bone within the grafted sinuses by hybrid HA\/TCP was significantly higher than those by xenografts (WMD 2.85, 95%CI [0.72; 4.99]), but those grafted by pure HA (WMD \u22121.72, 95%CI [\u22123.15; \u22120.29]) or TCP (WMD \u22127.10, 95%CI [\u221213.02; \u22121.17]) were significantly lower than xenograft counterparts. The residual bone graft and non\u2010mineralized tissue yielded by synthetic HA, TCP, and HA\/TCP showed no significant differences with the xenograft group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The chemistry of grafted bone substitutes in lateral MSFA influenced the quantity of newly formed bone. Those grafted with hybrid HA\/TCP yielded the highest amount of new bone compared to bovine\u2010originated HA. However, this influence was not significant on residual bone graft and non\u2010mineralized\u00a0tissue.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.13364","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T01:59:47Z","timestamp":1722304787000},"page":"1032-1045","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Bovine\u2010originated xenografts versus synthetic bone grafting materials in lateral maxillary sinus floor augmentation: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"26","author":[{"given":"Tianqi","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingxin","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinxin","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaji","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junyu","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6922-2918","authenticated-orcid":false,"given":"Hongchang","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"College of Stomatology Shanghai Jiao Tong University  Shanghai China"},{"name":"National Center for Stomatology  Shanghai China"},{"name":"National Clinical Research Center for Oral Diseases  Shanghai China"},{"name":"Shanghai Key Laboratory of Stomatology  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.01.001"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12768"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2008.05.012"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13055"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12275"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13147"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12694"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13058"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2010.02034.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12808"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.09.044"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2021.02.009"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2018.e00884"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2016.03.010"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/id.0000000000000768"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2016.04.020"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003583"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j4008"},{"key":"e_1_2_11_20_1","unstructured":"RyanR HillS.How to GRADE the quality of the evidence. Cochrane Consumers and Communication Group. Available at2016http:\/\/cccrgcochraneorg\/author-resourcesVersion 30 December 2016."},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2008.03.004"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028422"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100528.1998.tb01932.x"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753\u20104887.2012.00544.x"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.1990.tb01060.x"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119536604.ch23"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02318.x"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31827ca01a"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678\u20107757\u20102020\u20100568"},{"issue":"6","key":"e_1_2_11_31_1","first-page":"980","article-title":"Maxillary sinus augmentation with a porous synthetic hydroxyapatite and bovine\u2010derived hydroxyapatite: a comparative clinical and histologic study","volume":"22","author":"Mangano C","year":"2007","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2008.01565.x"},{"issue":"3","key":"e_1_2_11_33_1","first-page":"273","article-title":"Histomorphometric comparison of a biphasic bone ceramic to anorganic bovine bone for sinus augmentation: 6\u2010 to 8\u2010month postsurgical assessment of vital bone formation. A pilot study","volume":"28","author":"Froum SJ","year":"2008","journal-title":"Int J Periodontics Restorative Dent"},{"issue":"5","key":"e_1_2_11_34_1","first-page":"935","article-title":"Deproteinized bovine bone versus \u03b2\u2010tricalcium phosphate in sinus augmentation surgery: a comparative histologic and histomorphometric study","volume":"23","author":"Simunek A","year":"2008","journal-title":"Int J Oral Maxillofac Implants"},{"issue":"6","key":"e_1_2_11_35_1","first-page":"1093","article-title":"Clinical histology of microimplants placed in two different biomaterials","volume":"24","author":"Lindgren C","year":"2009","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708\u20108208.2010.00224.x"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/central\/CN\u201000835886\/full"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12374"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID\u2010JOI\u2010D\u201011\u201000061"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2012.02431.x"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1563\/aaid\u2010joi\u2010d\u201014\u201000273"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9489825"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.6778"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.7116"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.8211"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12964"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12396"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010019\u201003164\u20109"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708\u20108208.2012.00445.x"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2012.02522.x"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678\u20107757\u20102017\u20100296"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2017.11.016"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1080\/09506608.2016.1266744"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120785"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.06.022"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0955\u20102219(02)00263\u20107"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2010.02042.x"},{"issue":"1","key":"e_1_2_11_58_1","first-page":"BR24","article-title":"Histological comparison of autograft, allograft\u2010DBM, xenograft, and synthetic grafts in a trabecular bone defect: an experimental study in rabbits","volume":"16","author":"Athanasiou VT","year":"2010","journal-title":"Med Sci Monit"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201093033\u2010x"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40729\u2010023\u201000502\u20101"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.5403"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2018.09.003"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2016.09.004"}],"container-title":["Clinical Implant Dentistry and Related Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cid.13364","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T07:56:39Z","timestamp":1737100599000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cid.13364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,29]]},"references-count":62,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/cid.13364"],"URL":"https:\/\/doi.org\/10.1111\/cid.13364","archive":["Portico"],"relation":{},"ISSN":["1523-0899","1708-8208"],"issn-type":[{"value":"1523-0899","type":"print"},{"value":"1708-8208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,29]]},"assertion":[{"value":"2024-04-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}