{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T03:41:49Z","timestamp":1792381309025,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100008417","name":"Sweden and Martina","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008417","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Full\u2010arch immediate loading rehabilitations are now a widely used rehabilitation method that guarantees predictable medium\u2010 and long\u2010term results. Numerous factors can influence its success and stability in the medium and long term. Among these the implant\u2010abutment connection seems to play an important role, however there is still little information on which is the most suitable in this type of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The aim of the present multicenter split\u2010mouth controlled trial is to evaluate whether external hexagonal connections (EHC) and internal hexagonal connections (IHC) can influence success, bone resorption and peri\u2010implant parameters in immediate\u2010load full\u2010arch rehabilitations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Twenty patients were rehabilitated with immediately loaded fixed full\u2010arch rehabilitations. All the implants presented the same macro\u2010 and micro\u2010topography but different implant\u2010abutment connection. IHC were used in one randomly selected side of the jaw and EHC was used in the other side. Outcome measures were implant survival rate, peri\u2010implant marginal bone loss (MBL), plaque index (PI), probing depth (PD), and bleeding on probing (BoP) evaluated at 3, 6, 12, 36, and 72\u2010month post\u2010loading. Technical and biological complications were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 20 patients, 43 EHC and 40 IHC implants were placed. Between 32 and 72\u2009months of follow\u2010up two patients withdrew (died) and no implants were lost. The cumulative survival rate (CSR) was 97.44% for EHC implants and 97.22% for IHC implants. The MBL presented a resorption of 2\u2009mm in the EHC group and 1.9\u2009mm in the IHC group. No statistically significant differences were found between the two groups for any of the parameters at any time. No biological or technical complications were detected between the 36th and 72nd month of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>After 72\u2009months in function, both internal and external hexagon connections provided good clinical outcomes and were not associated with any significant difference in the clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cid.13416","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:43:36Z","timestamp":1730940216000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Internal and External Hexagon Connections in Immediately Loaded Full\u2010Arch Rehabilitations: A Multicenter Randomized Split\u2010Mouth Controlled Trial With a 6\u2010Year Follow\u2010Up"],"prefix":"10.1111","volume":"27","author":[{"given":"Francesco","family":"Bagnasco","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences (DISC), Division of Prosthodontics and Implant Prosthodontics Dentistry University of Genoa  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Menini","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences (DISC), Division of Prosthodontics and Implant Prosthodontics Dentistry University of Genoa  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8726-4145","authenticated-orcid":false,"given":"Paolo","family":"Pesce","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences (DISC), Division of Prosthodontics and Implant Prosthodontics Dentistry University of Genoa  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Gibello","sequence":"additional","affiliation":[{"name":"C.I.R. Dental School, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9495-1832","authenticated-orcid":false,"given":"Massimo","family":"Carossa","sequence":"additional","affiliation":[{"name":"C.I.R. Dental School, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Pera","sequence":"additional","affiliation":[{"name":"C.I.R. Dental School, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.11607\/ijp.3569"},{"issue":"2","key":"e_1_2_11_3_1","first-page":"169","article-title":"Evaluation of Internal and External Hexagon Connections in Immediately Loaded Full\u2010Arch Rehabilitations: A Within\u2010Person Randomised Split\u2010Mouth Controlled Trial","volume":"12","author":"Menini M.","year":"2019","journal-title":"International Journal of Oral Implantology"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2003.tb00010.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2014.09.002"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2014suppl.g4.3"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.9710"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.11607\/ijp.5804"},{"issue":"1","key":"e_1_2_11_9_1","first-page":"11","article-title":"The Long\u2010Term Efficacy of Currently Used Dental Implants: A Review and Proposed Criteria of Success","volume":"1","author":"Albrektsson T.","year":"1986","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511431252"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12437"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.13848"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2014suppl.g2.2"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(81)80077-4"},{"issue":"4","key":"e_1_2_11_15_1","first-page":"347","article-title":"Long\u2010Term Follow\u2010Up Study of Osseointegrated Implants in the Treatment of Totally Edentulous Jaws","volume":"5","author":"Adell R.","year":"1990","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"issue":"4","key":"e_1_2_11_16_1","first-page":"519","article-title":"Mechanics of the Implant\u2010Abutment Connection: An 8\u2010Degree Taper Compared to a Butt Joint Connection","volume":"15","author":"Merz B. 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