{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:49:53Z","timestamp":1790815793784,"version":"4.1.0"},"reference-count":74,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Maxillary sinus elevation is a critical procedure in dental implantology, often necessary to address bone deficiencies in the posterior maxilla. However, various medical conditions, local factors, and surgical complexities can significantly influence the outcomes. This article delves into the implications of systemic conditions such as smoking, diabetes, osteoporosis, antiresorptive and antiangiogenic medications, radiotherapy, immunocompromised states, cardiovascular diseases, chronic alcoholism, and oxidative stress on sinus floor elevation and associated dental implant placements. Each condition presents unique challenges and necessitates tailored clinical considerations to mitigate risks and enhance surgical success. A comprehensive pre\u2010operative assessment is essential, including detailed patient history and radiographic evaluation. Local conditions affecting the maxillary sinus, such as sinusitis, require careful examination and possible otolaryngologist consultation. The article discusses a standardized Digital Surgical Planning (DSP) protocol involving CBCT imaging, intraoral scans, virtual diagnostic wax\u2010ups, and guided implant placement to optimize surgical planning and outcomes. Surgical techniques for lateral window antrostomy are examined, including flap design, window size and location, and piezoelectric and rotary instrumentation. Subsequent regenerative procedures involve meticulous membrane elevation and particulate graft placement, with considerations for graft material and technique to ensure stability and volume retention. Post\u2010operative care, encompassing antibiotic prophylaxis, corticosteroid use, and decongestants, is outlined to prevent infections and manage edema. Conclusively, the article stresses the necessity for implantologists to be proficient in various techniques and make evidence\u2010based decisions tailored to individual patient needs, ensuring optimal implant therapy outcomes. The lateral window approach remains a cornerstone of regenerative dental procedures, maintaining its significance through evolving methodologies and clinical advances. The lateral window sinus elevation procedure has demonstrated consistent success as a pre\u2010prosthetic surgical intervention for over four decades, supported by multiple reviews. Initially a hospital\u2010based procedure requiring autogenous bone harvesting, it has evolved into a minimally invasive, office\u2010based procedure without the need for donor bone. Smaller access windows and flaps have further reduced morbidity. Despite the emergence of less invasive techniques such as the transcrestal approach and the use of tilted or short implants, the lateral window procedure remains relevant due to its unique advantages: Provides greater access to overcome obstacles like septa. Facilitates single\u2010surgery management of multiple implant sites. Remains applicable regardless of residual crestal bone height. Allows intraoperative management of complications such as membrane perforations.<\/jats:p>","DOI":"10.1111\/cid.70007","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T09:38:46Z","timestamp":1746783526000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Indications and Regenerative Techniques for Lateral Window Sinus Floor Elevation With Ridge Augmentation"],"prefix":"10.1111","volume":"27","author":[{"given":"Riccardo","family":"Scaini","sequence":"first","affiliation":[{"name":"IRCCS Galeazzi Sant'Ambrogio Hospital, Dental Clinic Section of Implant Dentistry and Oral Rehabilitation  Milan Italy"},{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-7317","authenticated-orcid":false,"given":"Muhammad H. A.","family":"Saleh","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong\u2010Chang","family":"Lai","sequence":"additional","affiliation":[{"name":"Ninth People Hospital and College of Stomatology Shanghai Jiao Tong University School of Medicine Shanghai  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Sangiorgi","sequence":"additional","affiliation":[{"name":"Periodontology Unit, Department of Biomedical and Neuromotor Sciences Bologna University  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Zucchelli","sequence":"additional","affiliation":[{"name":"Periodontology Unit, Department of Biomedical and Neuromotor Sciences Bologna University  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziano","family":"Testori","sequence":"additional","affiliation":[{"name":"IRCCS Galeazzi Sant'Ambrogio Hospital, Dental Clinic Section of Implant Dentistry and Oral Rehabilitation  Milan Italy"},{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor USA"},{"name":"Department of Oral Medicine Infection and Immunity Harvard University, School of Dental Medicine  Boston USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"613","article-title":"Grafting of the Maxillary Sinus Floor With Autogenous Marrow and Bone","volume":"38","author":"Boyne P. 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