{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T16:42:40Z","timestamp":1789836160297,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess the clinical and radiographic outcomes of computer\u2010aided design\u2013computer\u2010assisted manufacturing (CAD\u2010CAM) zirconia bars supporting mandibular implant overdentures (IODs) up to a follow\u2010up period of 3\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A prospective cohort observational single\u2010center study involving 30 edentulous patients rehabilitated with two dental implants (\u00d84.3\u2009\u00d7\u200910\u2009mm) at the crestal bone level and an IOD supported by a zirconia bar with distal extensions (maximum length 10.6\u2009mm). At the 1\u2010 and 3\u2010year follow\u2010up, implant, prosthetic survival, marginal bone level (MBL) changes, biological, and technical complications were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 25 patients were assessed at the 12\u2010month (dropout of 19.4%), and 14 patients completed the 36\u2010 month follow\u2010up (dropout of 54.8%). Implant survival and success rates were both 100%, while prosthetic survival was 100% with a success rate of 96%. No biological complications were observed during the follow\u2010up period; however, one patient exhibited generalized mucosal hyperplasia around the zirconia bar at the 12\u2010month evaluation. No prosthetic prosthodontic maintenance needs were reported. A mean marginal MBL of \u22121.28\u2009mm (SD\u2009\u00b1\u20090.37) was recorded at the initial 12\u2010month follow\u2010up, and \u2212\u20091.32\u2009mm (SD\u2009\u00b1\u20090.32) at the 36\u2010month follow\u2010up. The difference in MBL between the two time points was not statistically significant (<jats:italic>p<\/jats:italic>\u2009=\u20090.529).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Zirconia bars with distal extensions for mandibular IODs appear to be a reliable treatment option for the rehabilitation of edentulous patients, demonstrating favorable clinical outcomes up to 3\u2009years of follow\u2010up. A 100% implant and prosthetic survival rate was achieved, along with stable MBLs.<\/jats:p><jats:p>Clinicaltrials.gov identifier: NCT06471881.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cid.70066","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T11:25:33Z","timestamp":1753442733000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical and Radiographic Evaluation of Zirconia Bars for Mandibular Implant Overdentures: A Prospective Cohort Study With up to 3 Years of Follow\u2010Up"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5493-0295","authenticated-orcid":false,"given":"Pedro","family":"Molinero\u2010Mourelle","sequence":"first","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology School of Dental Medicine, University of Bern  Bern Switzerland"},{"name":"Department of Conservative Dentistry and Orofacial Prosthodontics Faculty of Dentistry, Complutense University of Madrid, Spain"},{"name":"Complutense University of Madrid, Ramon y Cajal Research Institute (IRYCIS)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4267-0515","authenticated-orcid":false,"given":"Manrique","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology School of Dental Medicine, University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc Emmanuel","family":"Grossen","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology School of Dental Medicine, University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9941-3491","authenticated-orcid":false,"given":"Anina N.","family":"Zuercher","sequence":"additional","affiliation":[{"name":"Clinic for Reconstructive Dentistry Center of Dental Medicine, University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9700-5534","authenticated-orcid":false,"given":"Martin","family":"Schimmel","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology School of Dental Medicine, University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joannis","family":"Katsoulis","sequence":"additional","affiliation":[{"name":"Department of Reconstructive Dentistry and Gerodontology School of Dental Medicine, University of Bern  Bern Switzerland"},{"name":"Department of Preventive and Restorative Sciences School of Dental Medicine, Robert Schattner Center, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12113760"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2022.104335"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016357.2021.2018494"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12769"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/08959374990130010101"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102842.2012.02340.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.12968\/denu.2006.33.3.134"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13668"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02213.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02283.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14065"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14145"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12130"},{"issue":"3","key":"e_1_2_10_15_1","first-page":"648","article-title":"Maintenance of Implant\u2010Supported Maxillary Prostheses: A 2\u2010Year Controlled Clinical Trial","volume":"26","author":"Katsoulis J.","year":"2011","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13761"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2013.07.004"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13164"},{"issue":"3","key":"e_1_2_10_19_1","first-page":"253","article-title":"Zirconia Bars for Mandibular Implant Overdentures: A 1\u2010Year Clinical and Radiographic Pilot Study","volume":"15","author":"Zuercher A. 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