{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:34:26Z","timestamp":1791819266475,"version":"4.3.4"},"reference-count":54,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the effects of maxillary sinus augmentation (MSA) using deproteinized bovine bone material (DBBM) combined with or without platelet\u2010rich fibrin obtained by horizontal centrifugation (H\u2010PRF) after a short healing period of 4\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Thirteen patients underwent bilateral two\u2010stage MSA using a split\u2010mouth model. Each side was randomly assigned to receive DBBM alone (control group) or DBBM\u2009+\u2009H\u2010PRF (test group). Bone tissue samples were harvested 4\u2009months after implant placement and evaluated using microcomputed tomography (micro\u2010CT), as well as histological and histomorphometric analyses. Data were statistically analyzed using paired\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests (Wilcoxon signed\u2010rank test;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Histomorphometric analysis demonstrated higher amounts (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) of newly formed bone in the DBBM\u2009+\u2009H\u2010PRF group compared to the control group (51.33%\u2009\u00b1\u20096.17% versus 45.68%\u2009\u00b1\u20096.65%, respectively). Micro\u2010CT also revealed significantly higher bone volume (30.38%\u2009\u00b1\u200911.24% and 21.38%\u2009\u00b1\u20099.83%, respectively) and connectivity density (4485\u2009\u00b1\u20091469 and 2562\u2009\u00b1\u20091271, respectively) in the DBBM\u2009+\u2009H\u2010PRF group than in the DBBM\u2010alone group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Compared with DBBM alone, maxillary sinuses augmented with H\u2010PRF combined with DBBM exhibited improved qualitative and quantitative new bone formation after 4\u2009months of healing. However, the effects on the long\u2010term survival and early stability of dental implants remain unknown and warrant further investigation with long\u2010term follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cid.70093","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:19:51Z","timestamp":1759411191000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Sinus Floor Elevation With Platelet\u2010Rich Fibrin From Horizontal Centrifugation and Xenograft: Randomized Clinical Trial"],"prefix":"10.1111","volume":"27","author":[{"given":"Gabriel Guerra David","family":"Reis","sequence":"first","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery and Periodontology Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo\u2014USP  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8312-7493","authenticated-orcid":false,"given":"Ricardo J\u00fanior","family":"Denardi","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery and Periodontology Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo\u2014USP  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Lu\u00eds Scombatti","family":"de Souza","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery and Periodontology Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo\u2014USP  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7583-7046","authenticated-orcid":false,"given":"Pedro Henrique Felix","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery and Periodontology Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo\u2014USP  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8072-3983","authenticated-orcid":false,"given":"Fl\u00e1via","family":"Furlaneto","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery and Periodontology Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo\u2014USP  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3290-3418","authenticated-orcid":false,"given":"Richard J.","family":"Miron","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5775-0222","authenticated-orcid":false,"given":"Carlos Fernando","family":"Mour\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Periodontology Tufts University School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8485-9645","authenticated-orcid":false,"given":"Michel Reis","family":"Messora","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery and Periodontology Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo\u2014USP  Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2016.09.004"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7267062"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/7589072"},{"issue":"8","key":"e_1_2_9_5_1","first-page":"613","article-title":"Grafting of the Maxillary Sinus Floor With Autogenous Marrow and Bone","volume":"38","author":"Boyne P. 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