{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:44:12Z","timestamp":1791863052325,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Implant Dent Rel Res"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This study investigated the impact of sinus membrane thickening and perforation on graft remodeling following osteotome sinus floor elevation (OSFE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      A total of 136 patients who received single implants with simultaneous OSFE were retrospectively analyzed and categorized based on preoperative sinus membrane thickness: membrane thickening (MT; &gt;\u20092\u2009mm,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200938) and normal thickness (NT; \u2264\u20092\u2009mm,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200998). Cone\u2010beam computed tomography was used to assess residual bone height and membrane thickness. Periapical radiographs obtained immediately postoperatively (T1) and at final follow\u2010up (T2) were used to quantify sinus bone gain and apical graft height. The incidence of membrane perforation and implant survival was also documented.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Implant survival rates were comparable between groups (MT: 97.4%, NT: 99.0%,\n                      <jats:italic>p\u2009=\u20090.485<\/jats:italic>\n                      ). The incidence of membrane perforation occurred significantly more frequently in the MT group than in the NT group (21.1% vs. 6.1%,\n                      <jats:italic>p\u2009=\u20090.010<\/jats:italic>\n                      ). Although final sinus bone gain was similar, apical graft resorption was significantly greater in the MT group compared to the NT group (2.3\u2009\u00b1\u20090.4\u2009mm vs. 1.8\u2009\u00b1\u20090.6\u2009mm;\n                      <jats:italic>p\u2009&lt;\u20090.001<\/jats:italic>\n                      ), resulting in a higher incidence of complete apical bone coverage loss (39.5% vs. 16.3%,\n                      <jats:italic>p\u2009=\u20090.004<\/jats:italic>\n                      ). Furthermore, membrane perforation increased apical graft resorption risk regardless of membrane thickness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sinus membrane thickening is associated with increased risk of perforation and greater apical graft resorption following OSFE. Thorough preoperative evaluation and careful surgical technique are essential to optimize outcomes, particularly in cases with thickened membranes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cid.70103","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T08:35:31Z","timestamp":1764146131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impact of Membrane Thickening and Perforation on Graft Remodeling After Osteotome Sinus Elevation: A Retrospective Study"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4112-9444","authenticated-orcid":false,"given":"Hsuan\u2010Hung","family":"Chen","sequence":"first","affiliation":[{"name":"Division of Periodontics, Department of Stomatology Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"School of Dentistry, National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5163-8909","authenticated-orcid":false,"given":"Yu\u2010Ming","family":"Kuo","sequence":"additional","affiliation":[{"name":"Division of Periodontics, Department of Stomatology Taipei Veterans General Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6400-9982","authenticated-orcid":false,"given":"Yi\u2010Chun","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Periodontics, Department of Stomatology Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"School of Dentistry, National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0988-1276","authenticated-orcid":false,"given":"Ya\u2010Chi","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Periodontics, Department of Stomatology Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"School of Dentistry, National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1290-9994","authenticated-orcid":false,"given":"Guo\u2010Hao","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Dentistry, National Yang Ming Chiao Tung University  Taipei Taiwan"},{"name":"Division of Periodontology, Department of Orofacial Sciences, School of Dentistry University of California San Francisco  San Francisco California USA"},{"name":"Department of Periodontics &amp; Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8601-6892","authenticated-orcid":false,"given":"Yu\u2010Lin","family":"Lai","sequence":"additional","affiliation":[{"name":"Division of Periodontics, Department of Stomatology Taipei Veterans General Hospital  Taipei Taiwan"},{"name":"School of Dentistry, National Yang Ming Chiao Tung University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708\u20108208.2011.00399.x"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.8.1237"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2024.05.006"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12464"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02321.x"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/id.0000000000000485"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.06.442"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2010.02140.x"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3007"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489009107468"},{"issue":"6","key":"e_1_2_13_12_1","first-page":"1128","article-title":"Correlation Between Gingival Phenotype and Schneiderian Membrane Thickness","volume":"23","author":"Aimetti M.","year":"2008","journal-title":"Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12856"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2016.160041"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489419883292"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12646"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13424"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12429"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(07)61602\u2010X"},{"issue":"6","key":"e_1_2_13_20_1","first-page":"599","article-title":"The Modified Osteotome Technique","volume":"21","author":"Davarpanah M.","year":"2001","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2020.12.010"},{"issue":"6","key":"e_1_2_13_22_1","first-page":"833","article-title":"Evaluation of Maxillary Sinus Membrane Response Following Elevation With the Crestal Osteotome Technique in Human Cadavers","volume":"16","author":"Reiser G. M.","year":"2001","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663\u2010021\u201001551\u2010y"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0000000000000798"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2016.160337"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13541"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12920"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2004.00988.x"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2004.00996.x"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.5125\/jkaoms.2014.40.3.117"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID\u2010JOI\u2010D\u201011\u201000160"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12893"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2009.01721.x"},{"issue":"4","key":"e_1_2_13_34_1","first-page":"466","article-title":"Reconstruction of the Severely Resorbed Maxilla With Dental Implants in the Augmented Maxillary Sinus: A 5\u2010Year Clinical Investigation","volume":"11","author":"Hurzeler M. B.","year":"1996","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.3206"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2008.01272.x"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2008.01273.x"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2020.05.018"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2016.08.003"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2017.160694"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010017\u20102201\u20104"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13038"}],"container-title":["Clinical Implant Dentistry and Related Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cid.70103","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cid.70103","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cid.70103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T11:22:58Z","timestamp":1773919378000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cid.70103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,26]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/cid.70103"],"URL":"https:\/\/doi.org\/10.1111\/cid.70103","archive":["Portico"],"relation":{},"ISSN":["1523-0899","1708-8208"],"issn-type":[{"value":"1523-0899","type":"print"},{"value":"1708-8208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,26]]},"assertion":[{"value":"2025-09-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70103"}}