{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T11:23:00Z","timestamp":1772018580397,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,4,2]],"date-time":"2013-04-02T00:00:00Z","timestamp":1364860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to assess the performance of zirconia implants under immediate loading compared with delayed loading in dogs over 30\u201390\u00a0days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Tooth extractions were made for the subsequent placement of dental implants at premolars P2, P3, P4 and molars M1 bilaterally in the dog mandible. Forty eight zirconia implants, 4\u00a0mm in diameter and 10\u00a0mm in length, were inserted, whose neck and body surfaces had been treated with femtosecond laser texturing; 24 implants were loaded immediately and 24 remained unloaded during the osseointegration period. Final radiographs were taken recording stability values before sacrifice at 30 or 90\u00a0days when sample removal for histological and histomorphometric analysis was performed. Bone\u2010to\u2010implant contact, crestal bone loss and implant stability were evaluated at these two study times.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bone\u2010to\u2010implant contact values after 30\u00a0days were 38.9% for immediately loaded implants and 32% for non\u2010loaded implants. After 90\u00a0days, values increased to 65% for immediately loaded and 57.6% for non\u2010loaded implants. After 30\u00a0days, there was more crestal bone lost in the non\u2010loaded group (0.58\u00a0\u00b1\u00a00.28\u00a0mm) compared with the immediately loaded group (0.5\u00a0\u00b1\u00a00.3\u00a0mm). After 90\u00a0days, there was improved stability in both groups, but was lower in the immediately loaded group (0.5\u00a0\u00b1\u00a00.23\u00a0mm) compared with the non\u2010loaded group (0.56\u00a0\u00b1\u00a00.28\u00a0mm). Initial implant stability values were \u22123.5 <jats:styled-content style=\"fixed-case\">PTV<\/jats:styled-content> at the moment of implant placement. Stability values after the first 30\u00a0days were \u22124 for immediately loaded implants and \u22123 for non\u2010loaded. At 90\u00a0days, non\u2010loaded implants showed \u22124.9, whereas immediately loaded showed \u22127.1.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>For the different parameters studied, zirconia implants treated with femtosecond laser and subjected to immediate loading showed better results compared with non\u2010loaded implants in terms of <jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>, crestal bone loss and implant stability.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12145","type":"journal-article","created":{"date-parts":[[2013,4,3]],"date-time":"2013-04-03T02:37:44Z","timestamp":1364956664000},"page":"826-830","source":"Crossref","is-referenced-by-count":21,"title":["Histological, radiological and histomorphometric evaluation of immediate vs. non\u2010immediate loading of a zirconia implant with surface treatment in a dog model"],"prefix":"10.1111","volume":"25","author":[{"given":"Jose L.","family":"Calvo\u2010Guirado","sequence":"first","affiliation":[{"name":"Department of Implant Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Aguilar\u2010Salvatierra","sequence":"additional","affiliation":[{"name":"Department of Pharmacological Research in Dentistry and Special Care Faculty of Dentistry University of Granada Granada Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Gomez\u2010Moreno","sequence":"additional","affiliation":[{"name":"Department of Pharmacological Research in Dentistry and Special Care Faculty of Dentistry University of Granada Granada Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Guardia","sequence":"additional","affiliation":[{"name":"Department of Pharmacological Research in Dentistry and Special Care Faculty of Dentistry University of Granada Granada Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael A.","family":"Delgado\u2010Ruiz","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Eduardo","family":"Mate\u2010Sanchez de Val","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry Faculty of Medicine and Dentistry University of Murcia Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2007.00247.x"},{"key":"e_1_2_6_3_1","first-page":"1108","article-title":"Immediate, early, and late implant placement in first\u2010molar sites: A retrospective case series","volume":"26","author":"Annibali S.","year":"2011","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01365.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2008.00135.x"},{"key":"e_1_2_6_6_1","first-page":"8","article-title":"Evaluation of periimplant bone neoformation using different scanning electron microscope methods for measuring BIC. 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