{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T15:36:20Z","timestamp":1767972980252,"version":"3.49.0"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,9,22]],"date-time":"2013-09-22T00:00:00Z","timestamp":1379808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To assess the influence of an activated implant surface and a synthetic graft material in the maxillary sinus in combination with sinus floor elevation on bone\u2010to\u2010implant contact (<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>) as compared to implants with conventional surfaces.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>In 16 sheep, sinus bone augmentation was performed using a synthetic bone graft material according to the methods described by Haas et\u00a0al (<jats:italic>Clinical Oral Implants Research,<\/jats:italic><jats:bold>9<\/jats:bold>, 1998, 107;<jats:italic>Clinical Oral Implants Research,<\/jats:italic><jats:bold>13<\/jats:bold>, 2002, 396). Another 16 sheep received a sinus floor elevation procedure without graft material. Using a paired design, in one sinus of each animal, a conventional implant was placed, whereas an implant with activated surface was placed in the other. Eight animals of each group were sacrificed at 12\u00a0weeks and the others at 26\u00a0weeks after surgery. Histological analysis was performed to analyse<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>. Results were statistically compared at a significance level of<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 12\u00a0weeks, the<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>for conventional and activated implants with or without graft showed comparable results, with mean values of 14.8%, 16.5%, 21.5% and 20.1% (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). For ungrafted sinuses after 26\u00a0weeks, no increase in<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>was recorded (12.1% conventional surface, 15.8% activated surface;<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). In grafted sinuses after 26\u00a0weeks, mean values increased to 28.7% for conventional and 34.1% for activated implants (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.014;<jats:italic>P<\/jats:italic>\u00a0=\u00a00.015). However, only<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>of the latter was statistically significantly higher compared with ungrafted sinuses (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.038).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>After 12\u00a0weeks of healing, neither grafting nor implant type seemed to influence<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>. Use of an activated implant surface did not increase<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>when compared with a conventional implant. The synthetic graft seemed to improve<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>values after 26\u00a0weeks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12255","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T22:07:58Z","timestamp":1381529278000},"page":"1142-1148","source":"Crossref","is-referenced-by-count":26,"title":["Comparison of<scp>SLA<\/scp><sup>\u00ae<\/sup>or<scp>SLA<\/scp>ctive<sup>\u00ae<\/sup>implants placed in the maxillary sinus with or without synthetic bone graft materials \u2013 an animal study in sheep"],"prefix":"10.1111","volume":"25","author":[{"given":"Alexander","family":"Philipp","sequence":"first","affiliation":[{"name":"Clinic of Fixed and Removable Prosthodontics and Dental Materials Science University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warwick","family":"Duncan","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute School of Dentistry University of Otago Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malgorzata","family":"Roos","sequence":"additional","affiliation":[{"name":"Division of Biostatistics Institute of Social and Preventive Medicine University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph H.","family":"H\u00e4mmerle","sequence":"additional","affiliation":[{"name":"Clinic of Fixed and Removable Prosthodontics and Dental Materials Science University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Attin","sequence":"additional","affiliation":[{"name":"Clinic of Preventive Dentistry, Periodontology and Cariology University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick R.","family":"Schmidlin","sequence":"additional","affiliation":[{"name":"Clinic of Preventive Dentistry, Periodontology and Cariology University of Zurich Zurich Switzerland"},{"name":"Sir John Walsh Research Institute School of Dentistry University of Otago Dunedin New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,22]]},"reference":[{"key":"e_1_2_6_2_1","author":"An Y","year":"1999","journal-title":"Animal Models in Orthopaedic Research"},{"key":"e_1_2_6_3_1","first-page":"613","article-title":"Grafting of the maxillary sinus floor with autogenous marrow and bone","volume":"38","author":"Boyne P.J.","year":"1980","journal-title":"Journal of Oral Surgery"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2007.00050.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910408300704"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.12.1523"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.02096.x"},{"key":"e_1_2_6_8_1","first-page":"7","article-title":"Effectiveness of sinus lift procedures for dental implant rehabilitation: a Cochrane systematic review","volume":"3","author":"Esposito M.","year":"2010","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01557.x"},{"key":"e_1_2_6_10_1","first-page":"1037","article-title":"Biomechanical comparison of different surface modifications for dental implants","volume":"23","author":"Ferguson S.","year":"2008","journal-title":"International Journal or Oral & Maxillofacial Implants"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01821.x"},{"key":"e_1_2_6_12_1","first-page":"273","article-title":"Histomorphometric comparison of a biphasic bone ceramic to anorganic bovine bone for sinus augmentation: 6\u2010 to 8\u2010month postsurgical assessment of vital bone formation. 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