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Twenty\u2010four implants were placed. The right side sinus (Group 1) was grafted with biphasic calcium phosphate (<jats:styled-content style=\"fixed-case\">BCP<\/jats:styled-content>), whereas the left side (Group 2) was left without any grafting materials. The animals were euthanized 8 and 24\u00a0weeks after surgery for histological and histomorphometric assessment. Bone\u2010to\u2010implant contact (<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>%), alveolar bone height (<jats:styled-content style=\"fixed-case\">ABH<\/jats:styled-content>), bone density (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>) and grafting material density (<jats:styled-content style=\"fixed-case\">GMD<\/jats:styled-content>) were measured. The implant stability (<jats:styled-content style=\"fixed-case\">ISQ<\/jats:styled-content>) was assessed using resonance frequency analysis (<jats:styled-content style=\"fixed-case\">RFA<\/jats:styled-content>) at implant placement and 1, 2, 4, 8, 12, 24\u00a0weeks after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Endo\u2010sinus new bone with direct contact to implant surface were observed in two groups at both time points. <jats:styled-content style=\"fixed-case\">ABH<\/jats:styled-content> showed no difference between groups at both time points. <jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>% and <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> in Group 2 (40.05%, 35.90%) was higher than those in Group 1 (23.30%,25.59%) at 24\u00a0weeks. Significant shrinkage of grafting material was seen in Group 1. The <jats:styled-content style=\"fixed-case\">GMD<\/jats:styled-content> in Group 1 at 8\u00a0weeks was 24.35%, while it dropped to 19.90% at 24\u00a0weeks. The changing pattern of <jats:styled-content style=\"fixed-case\">ISQ<\/jats:styled-content> for both groups were similar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Spontaneous new bone formation and better bone\u2010to\u2010implant contact were found for <jats:styled-content style=\"fixed-case\">OSFE<\/jats:styled-content> without grafting. The grafting material application during <jats:styled-content style=\"fixed-case\">OSFE<\/jats:styled-content> procedure showed no advantages in histological results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12313","type":"journal-article","created":{"date-parts":[[2013,12,21]],"date-time":"2013-12-21T05:02:51Z","timestamp":1387602171000},"page":"197-203","source":"Crossref","is-referenced-by-count":20,"title":["Osteotome sinus floor elevation with and without grafting: an animal study in Labrador dogs"],"prefix":"10.1111","volume":"26","author":[{"given":"Mi\u2010Si","family":"Si","sequence":"first","affiliation":[{"name":"Department of Oral and Maxilliofacial Implantology Shanghai Ninth People's Hospital School of Medicine Shanghai Institute of Stomatology Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2010Ji","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxilliofacial Implantology Shanghai Ninth People's Hospital School of Medicine Shanghai Institute of Stomatology Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long\u2010Fei","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry the University of Hong Kong Sai Ying Pun Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying\u2010Xin","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxilliofacial Implantology Shanghai Ninth People's Hospital School of Medicine Shanghai Institute of Stomatology Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi\u2010Chong","family":"Qiao","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxilliofacial Implantology Shanghai Ninth People's Hospital School of Medicine Shanghai Institute of Stomatology Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong\u2010Chang","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxilliofacial Implantology Shanghai Ninth People's Hospital School of Medicine Shanghai Institute of Stomatology Shanghai Jiaotong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02385.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2002.130409.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(97)00018-5"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01565.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.02096.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01557.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2007.00062.x"},{"key":"e_1_2_6_9_1","first-page":"273","article-title":"Histomorphometric comparison of a biphasic bone ceramic to anorganic bovine bone for sinus augmentation: 6\u2010 to 8\u2010month postsurgical assessment of vital bone formation. 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