{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:36:17Z","timestamp":1791891377412,"version":"4.3.4"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T00:00:00Z","timestamp":1388707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Junta de Andaluc\u00eda Funding Program","award":["#CTS-138"],"award-info":[{"award-number":["#CTS-138"]}]},{"name":"Junta de Andaluc\u00eda Funding Program","award":["CTS-583"],"award-info":[{"award-number":["CTS-583"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      The aim of this study was to analyze marginal bone loss (\n                      <jats:styled-content style=\"fixed-case\">MBL<\/jats:styled-content>\n                      ) rates around implants to establish the difference between physiological bone loss and bone loss due to peri\u2010implantitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      Five hundred and eight implants were placed in the posterior maxilla in 208 patients. Data were gathered on age, gender, bone substratum (grafted or pristine), prosthetic connection, smoking and alcohol habits, and previous periodontitis.\n                      <jats:styled-content style=\"fixed-case\">MBL<\/jats:styled-content>\n                      was radiographically analyzed in three time frames (5\u00a0months post\u2010surgery and at 6 and 18\u00a0months post\u2010loading). Nonparametric receiver operating curve (\n                      <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>\n                      ) analysis and mixed linear model analysis were used to determine whether implants could be classified as high or low bone loser type (\n                      <jats:styled-content style=\"fixed-case\">BLT<\/jats:styled-content>\n                      ) and to establish the influence of this factor on\n                      <jats:styled-content style=\"fixed-case\">MBL<\/jats:styled-content>\n                      rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Marginal bone loss rates were significantly affected by\n                      <jats:styled-content style=\"fixed-case\">BLT<\/jats:styled-content>\n                      , connection type, bone substratum, and smoking. Bone loss rates at 18\u00a0months were associated with initial bone loss rates: 96% of implants with an\n                      <jats:styled-content style=\"fixed-case\">MBL<\/jats:styled-content>\n                      of &gt;2\u00a0mm at 18\u00a0months had lost 0.44\u00a0mm or more at 6\u00a0months post\u2010loading.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Implants with increased\n                      <jats:styled-content style=\"fixed-case\">MBL<\/jats:styled-content>\n                      rates at early stages (healing and immediate post\u2010loading periods) are likely to reach\n                      <jats:styled-content style=\"fixed-case\">MBL<\/jats:styled-content>\n                      values that compromise their final outcome. Initial (healing, immediate post\u2010loading)\n                      <jats:styled-content style=\"fixed-case\">MBL<\/jats:styled-content>\n                      rates around an implant of more than 0.44\u00a0mm\/year are an indication of peri\u2010implant bone loss progression.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/clr.12324","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T00:52:16Z","timestamp":1388710336000},"source":"Crossref","is-referenced-by-count":227,"title":["Marginal bone loss as success criterion in implant dentistry: beyond 2\u00a0mm"],"prefix":"10.1111","volume":"26","author":[{"given":"Pablo","family":"Galindo\u2010Moreno","sequence":"first","affiliation":[{"name":"Oral Surgery and Implant Dentistry Department School of Dentistry University of Granada Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Le\u00f3n\u2010Cano","sequence":"additional","affiliation":[{"name":"Oral Surgery and Implant Dentistry Department School of Dentistry University of Granada Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inmaculada","family":"Ortega\u2010Oller","sequence":"additional","affiliation":[{"name":"Oral Surgery and Implant Dentistry Department School of Dentistry University of Granada Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Monje","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine School of Dentistry University of Michigan Ann Arbor USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"O\u2032Valle","sequence":"additional","affiliation":[{"name":"Department of Pathology School of Medicine &amp; 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