{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:00:26Z","timestamp":1790283626222,"version":"4.1.0"},"reference-count":56,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T00:00:00Z","timestamp":1397520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This investigation focused on histological characteristics and 5\u2010year implant survival after sinus floor augmentation with anorganic bovine bone (<jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content>, Bio\u2010Oss<jats:sup>\u00ae<\/jats:sup>) and <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> plus autologous bone (<jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>) with a ratio of 1\/1.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Nineteen consecutive patients with bony atrophy of the posterior edentulous maxilla and a vertical bone height \u22644\u00a0mm were prospectively included in this study. In the first surgical stage, the maxillary sinus was non\u2010randomized either augmented with <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> alone (<jats:italic>n\u00a0<\/jats:italic>=\u00a012) or a 1\/1 mixture of <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> (<jats:italic>n\u00a0<\/jats:italic>=\u00a07). After a mean healing period of 167\u00a0days, biopsies were harvested in the region of the grafted sinus with a trephine burr and implants were placed simultaneously, <jats:styled-content style=\"fixed-case\">ABB <\/jats:styled-content><jats:italic>n\u00a0<\/jats:italic>=\u00a018 and <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">AB <\/jats:styled-content><jats:italic>n\u00a0<\/jats:italic>=\u00a012. The samples were microradiographically and histomorphometrically analyzed judging the newly formed bone (bone volume, <jats:styled-content style=\"fixed-case\">BV<\/jats:styled-content>), residual bone substitute material volume (<jats:styled-content style=\"fixed-case\">BSMV<\/jats:styled-content>), and intertrabecular volume (soft tissue volume, <jats:styled-content style=\"fixed-case\">ITV<\/jats:styled-content>) in the region of the augmented maxillary sinus. Implant survival was retrospectively evaluated from patient's records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant difference in residual bone substitute material (<jats:styled-content style=\"fixed-case\">BSMV<\/jats:styled-content>) in the <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> group (31.21\u00a0\u00b1\u00a07.74%) and the group with the mixture of <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> (28.41\u00a0\u00b1\u00a08.43%) was histomorphologically determined. Concerning the de novo bone formation, also both groups showed statistically insignificant outcomes; <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> 26.02\u00a0\u00b1\u00a05.23% and <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> 27.50\u00a0\u00b1\u00a06.31%. In all cases, implants were installed in the augmented sites with sufficient primary stability. After a mean time in function of 5\u00a0years and 2\u00a0months, implant survival was 93.75% in the <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> and 92.86% in the <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> group with no statistically significant differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The usage of <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> plus <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> to a 1\/1 ratio leads to an amount of newly formed bone comparable with the solitary use of <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> after grafting of the maxillary sinus. Considering that <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content> is a non\u2010resorbable bone substitute, it can be hypothesized that this leads to stable bone over time and long\u2010term implant success. Importantly, in the sole use of <jats:styled-content style=\"fixed-case\">ABB<\/jats:styled-content>, bone grafting and therefore donor site morbidities can be avoided.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12396","type":"journal-article","created":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T06:26:40Z","timestamp":1397543200000},"page":"1043-1050","source":"Crossref","is-referenced-by-count":65,"title":["Anorganic bovine bone (<scp>ABB<\/scp>) vs. autologous bone (<scp>AB<\/scp>) plus <scp>ABB<\/scp> in maxillary sinus grafting. A prospective non\u2010randomized clinical and histomorphometrical trial"],"prefix":"10.1111","volume":"26","author":[{"given":"Christian M.","family":"Schmitt","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Erlangen\u2010Nuremberg Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3763-3122","authenticated-orcid":false,"given":"Tobias","family":"Moest","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Erlangen\u2010Nuremberg Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0199-9437","authenticated-orcid":false,"given":"Rainer","family":"Lutz","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Erlangen\u2010Nuremberg Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedrich W.","family":"Neukam","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Erlangen\u2010Nuremberg Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl Andreas","family":"Schlegel","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Erlangen\u2010Nuremberg Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01234.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198304000-00005"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0030-5898(20)30382-5","article-title":"Biology of bone transplantation","volume":"18","author":"Burchardt H.","year":"1987","journal-title":"The Orthopedic Clinics of North America"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01555.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01565.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090477"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0b013e3180de4c5f"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2008.00571.x"},{"key":"e_1_2_6_10_1","first-page":"565","article-title":"Systematic review of survival rates for implants placed in the grafted maxillary sinus","volume":"24","author":"Fabbro M.","year":"2004","journal-title":"The International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_11_1","first-page":"7","article-title":"Effectiveness of sinus lift procedures for dental implant rehabilitation: a cochrane systematic review","volume":"3","author":"Esposito M.","year":"2010","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_6_12_1","first-page":"273","article-title":"Histomorphometric comparison of a biphasic bone ceramic to anorganic bovine bone for sinus augmentation: 6\u2010 to 8\u2010month postsurgical assessment of vital bone formation. 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