{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:49:24Z","timestamp":1759402164129,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,9,27]],"date-time":"2014-09-27T00:00:00Z","timestamp":1411776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIH-NIDCR","award":["K23DE18414","DE06672"],"award-info":[{"award-number":["K23DE18414","DE06672"]}]},{"name":"Ivoclar Vivadent"},{"DOI":"10.13039\/501100009891","name":"DENTSPLY Implants","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009891","id-type":"DOI","asserted-by":"crossref"}]},{"name":"UF Office of Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>(1) To assess whether there is evidence of an association between the number of peri\u2010implant tissue complications and patient characteristics such as gender, diabetes status, smoking status, and bite force; (2) To assess whether there is evidence of an association between the number of peri\u2010implant tissue complications and location of the implant, surgical technique used, bone graft status and sinus lift status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This randomized, controlled clinical trial included a total of 176 implants (OsseoSpeed, DENTSPLY) in 67 participants with 88 fixed dental prostheses. Information was obtained from health histories, a baseline exam, surgical notes, and post\u2010operative exams. The data were analyzed using Fisher's exact and Mann\u2013Whitney tests and generalized estimating equations using logistic regression with a significance level set at 0.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 176 implants survived within a recall period of 3\u00a0years, but 11 implants demonstrated peri\u2010implant tissue complications. Ten sites showed dehiscence and one case exhibited vertical bone loss. There was a statistically significant association between surgical technique used (1\u2010stage or 2\u2010stage) and the presence of soft tissue complications (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005), where 2\u2010stage surgery was associated with a higher frequency of peri\u2010implant soft tissue complications. A correlation, although not statistically significant (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.077), was noted, between peri\u2010implant tissue complications and bone grafting, suggesting a possible role for this factor as well.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Participants who did not require any second\u2010stage surgery at the implant sites experienced fewer complications. Therefore, additional surgical procedures should be performed judiciously considering their possible effects on peri\u2010implant tissue health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical significance<\/jats:title><jats:p>The clinical implication of this research study is that secondary surgery should be considered with caution during implant placement and it should be performed only when other options have been exhausted, as it has been shown to have a direct adverse effect on the long\u2010term peri\u2010implant tissue health.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12484","type":"journal-article","created":{"date-parts":[[2014,9,27]],"date-time":"2014-09-27T08:57:37Z","timestamp":1411808257000},"page":"1390-1396","source":"Crossref","is-referenced-by-count":8,"title":["Peri\u2010implant complications for posterior endosteal implants"],"prefix":"10.1111","volume":"26","author":[{"given":"Josephine","family":"Esquivel\u2010Upshaw","sequence":"first","affiliation":[{"name":"Department of Restorative Dental Sciences College of Dentistry University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Mehler","sequence":"additional","affiliation":[{"name":"Department of Restorative Dental Sciences College of Dentistry University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Restorative Dental Sciences College of Dentistry University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Neal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery College of Medicine University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz","family":"Gonzaga","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery College of Dentistry University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Anusavice","sequence":"additional","affiliation":[{"name":"Department of Restorative Dental Sciences College of Dentistry University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,27]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"11","article-title":"The long\u2010term efficacy of currently used dental implants: a review and proposed criteria of success","volume":"1","author":"Albrektsson T.","year":"1986","journal-title":"The International journal of oral & maxillofacial 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