{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:57:41Z","timestamp":1789750661768,"version":"4.0.1"},"reference-count":47,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,2,26]],"date-time":"2015-02-26T00:00:00Z","timestamp":1424908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this randomized clinical trial was to analyse and compare the volumetric changes after ridge preservation procedures using two different biomaterials and to evaluate associations between outcome variables and pristine three\u2010dimensional aspects of the ridges.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Twenty\u2010eight patients subjected to single\u2010tooth alveolar ridge preservation were enrolled in the present multicentre, single\u2010blind, prospective and randomized clinical trial. Fourteen sites were randomly allocated to each experimental group. The experimental sites were grafted with pre\u2010hydrated collagenated cortico\u2010cancellous porcine bone (<jats:italic>coll<\/jats:italic> group) or with a cortical porcine bone (<jats:italic>cort<\/jats:italic> group) and a collagen membrane; a secondary soft tissue healing was obtained for all experimental sites. Plaster casts were scanned (preoperative, at 1 and 3\u00a0months postoperative). Analysis of volumes and areas was performed, and all measured variables were statistically compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Intragroup analyses at 3\u00a0months revealed that when examining changes related to three\u2010dimensional features of remodelling patterns (volume, surfaces, height and shape), the two biomaterials showed similar behaviours with a minor loss in volume and ridge surface. Intergroup analysis at 3\u2010month survey revealed that volume resorption of the <jats:italic>coll<\/jats:italic> group (244\u00a0mm<jats:sup>3<\/jats:sup>) was significantly lower (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.0140) than that of the <jats:italic>cort<\/jats:italic> group (349\u00a0mm<jats:sup>3<\/jats:sup>). The reduction for basal surface appeared significantly different between the two groups at 1\u2010month survey only (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.0137), while the final basal surface reduction was 4.9 and 12.2\u00a0mm<jats:sup>2<\/jats:sup> for <jats:italic>coll<\/jats:italic> and <jats:italic>cort<\/jats:italic> group, respectively. The superior surface reduction was 40.8\u00a0mm<jats:sup>2<\/jats:sup> for <jats:italic>coll<\/jats:italic> and 50.7\u00a0mm<jats:sup>2<\/jats:sup> for <jats:italic>cort<\/jats:italic> group, with no significant difference between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>At the 3rd month analysis, <jats:italic>coll<\/jats:italic> group showed a significantly lower reduction of ridge volume and a significantly smaller shrinkage of the basal area when compared to the <jats:italic>cort<\/jats:italic> group; moreover, the <jats:italic>coll<\/jats:italic> group experienced a smaller superior surface shrinkage when compared to the <jats:italic>cort<\/jats:italic> group, even though no significance was evaluated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12572","type":"journal-article","created":{"date-parts":[[2015,2,26]],"date-time":"2015-02-26T11:54:14Z","timestamp":1424951654000},"source":"Crossref","is-referenced-by-count":30,"title":["Volumetric analysis of remodelling pattern after ridge preservation comparing use of two types of xenografts. A multicentre randomized clinical trial"],"prefix":"10.1111","volume":"27","author":[{"given":"Antonio","family":"Barone","sequence":"first","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa Pisa Italy"},{"name":"Tuscan Stomatologic Institute Versilia General Hospital Lido di Camaiore (LU) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Toti","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa Pisa Italy"},{"name":"Tuscan Stomatologic Institute Versilia General Hospital Lido di Camaiore (LU) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Quaranta","sequence":"additional","affiliation":[{"name":"Department of Odontology and Specialized Clinical Sciences (DISCO) Marche Polytechnic University Torrette di Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fortunato","family":"Alfonsi","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa Pisa Italy"},{"name":"Tuscan Stomatologic Institute Versilia General Hospital Lido di Camaiore (LU) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Cucchi","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Verona Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose L.","family":"Calvo\u2010Guirado","sequence":"additional","affiliation":[{"name":"Department of Implantology University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Negri","sequence":"additional","affiliation":[{"name":"Department of Implantology University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Di Felice","sequence":"additional","affiliation":[{"name":"Private Practice Ascoli Piceno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"Covani","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa Pisa Italy"},{"name":"Tuscan Stomatologic Institute Versilia General Hospital Lido di Camaiore (LU) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070628"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02535.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2013.120711"},{"key":"e_1_2_5_5_1","first-page":"175","article-title":"Bone dimensions in the posterior mandible: a retrospective radiographic study using cone beam computed tomography. 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