{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:20:59Z","timestamp":1790828459292,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,10,31]],"date-time":"2015-10-31T00:00:00Z","timestamp":1446249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Qassim University, College of Dentistry, Saudi Arabia"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aims of this study were (i) to evaluate the efficacy of ridge preservation and repair procedures involving the application of Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> and Socket<jats:styled-content style=\"fixed-case\">KAGE<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> devices following tooth removal and (ii) to evaluate alveolar bone volumetric changes at 6\u00a0months post\u2010extraction in intact sockets or those with facial wall dehiscence defects using 3\u2010dimensional pre\u2010 and postoperative <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Thirty\u2010six patients required 61 teeth extracted. Five cohorts were established: Group A: Intact Socket Negative Control Group B: Intact Socket + Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> Group C: Intact Socket Filled with Anorganic Bovine Bone Mineral (<jats:styled-content style=\"fixed-case\">ABBM<\/jats:styled-content>) + Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> Group D: Facial Dehiscence Socket Negative Control Group E: Facial Dehiscence Socket Filled with <jats:styled-content style=\"fixed-case\">ABBM<\/jats:styled-content> + Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> + Socket<jats:styled-content style=\"fixed-case\">KAGE<\/jats:styled-content><jats:sup>\u2122<\/jats:sup>. Preoperative <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> scans were obtained followed by digital subtraction of the test teeth. At 6\u00a0months post\u2010extraction, another <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> scan was obtained. The pre\u2010 and postoperative scans were then superimposed, allowing highly accurate quantitative determination of the 3D volumetric alveolar bone volume changes from baseline through 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significant volumetric bone loss occurred in all sockets, localized mainly in the 0\u20133\u00a0mm zone apical to the ridge crest. For intact sockets, Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> + <jats:styled-content style=\"fixed-case\">ABBM<\/jats:styled-content> treatment led to a statistically significant greater percentage of remaining mineralized tissue volume when compared to negative control group. A significant difference favoring Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> + Socket<jats:styled-content style=\"fixed-case\">KAGE<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> + <jats:styled-content style=\"fixed-case\">ABBM<\/jats:styled-content> treatment was observed for sockets with facial dehiscence defects compared to the negative control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup>, with <jats:styled-content style=\"fixed-case\">ABBM<\/jats:styled-content>, appears effective in limiting post\u2010extraction volumetric bone loss in intact sockets, while Socket<jats:styled-content style=\"fixed-case\">KAP<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> + Socket<jats:styled-content style=\"fixed-case\">KAGE<\/jats:styled-content> + <jats:styled-content style=\"fixed-case\">ABBM<\/jats:styled-content> appears effective in limiting post\u2010extraction bone loss in sockets with dehiscence defects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12687","type":"journal-article","created":{"date-parts":[[2015,10,31]],"date-time":"2015-10-31T09:12:17Z","timestamp":1446282737000},"page":"631-639","source":"Crossref","is-referenced-by-count":23,"title":["An open randomized controlled clinical trial to evaluate ridge preservation and repair using Socket<scp>KAP<\/scp><sup>\u2122<\/sup> and Socket<scp>KAGE<\/scp><sup>\u2122<\/sup>: part 2 \u2013 three\u2010dimensional alveolar bone volumetric analysis of <scp>CBCT<\/scp> imaging"],"prefix":"10.1111","volume":"27","author":[{"given":"Alaa","family":"Abdelhamid","sequence":"first","affiliation":[{"name":"Dental Research Center (DRC) and Tissue Engineering and Biomaterials Research Unit (TEBRU) Qassim College of Dentistry Qassim University Buraidah Saudi 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