{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:41:08Z","timestamp":1789594868213,"version":"build-2803163510"},"reference-count":57,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,9,16]],"date-time":"2015-09-16T00:00:00Z","timestamp":1442361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004799","name":"Australian Dental Research Foundation","doi-asserted-by":"publisher","award":["2010001012"],"award-info":[{"award-number":["2010001012"]}],"id":[{"id":"10.13039\/501100004799","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2016,7]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To histomorphometrically compare the use of collagen\u2010stabilized anorganic bovine bone (ABBM<\/jats:styled-content>\u2010C) (test) to anorganic bovine bone\u00a0+\u00a0autogenous bone (ABBM<\/jats:styled-content>\u00a0+\u00a0AB<\/jats:styled-content>) (control) in maxillary sinus augmentation.<\/jats:p><\/jats:sec>Materials and Methods<\/jats:title>Forty (n<\/jats:italic>\u00a0=\u00a040 sinuses) patients underwent sinus augmentation and received either control (20 sinuses) or test bone graft (20 sinuses). Bone samples were harvested from the augmented sinuses 5\u00a0months postgrafting. The samples were processed for histomorphometry, which assessed within the primary region of interest (ROI<\/jats:styled-content>\u20101), the area fraction of new bone (%NB<\/jats:styled-content>), graft particle osseointegration (% OI<\/jats:styled-content>), residual graft (%RG<\/jats:styled-content>), and soft tissue components (% STM<\/jats:styled-content>). The same analysis was also carried out in a second region of interest (ROI<\/jats:styled-content>\u20102) located in a zone 1\u00a0mm proximal to the previous maxillary sinus floor.<\/jats:p><\/jats:sec>Results<\/jats:title>In both ROI<\/jats:styled-content>\u20101 and ROI<\/jats:styled-content>\u20102, the mean % NB<\/jats:styled-content>, %RG<\/jats:styled-content>, and %STM<\/jats:styled-content> in the control group were similar to mean values in the test group. The % OI<\/jats:styled-content> was significantly greater in the control group (42.0 +\/\u2212 26.8) when compared to the test group (19.6 +\/\u2212 27.3) in ROI<\/jats:styled-content>\u20102 (P<\/jats:italic>\u00a0<\u00a00.05). No statistically significant differences were seen when ROI<\/jats:styled-content>\u20101 and ROI<\/jats:styled-content>\u20102 were compared except for improved %OI<\/jats:styled-content> in ROI<\/jats:styled-content>\u20102 in the control group. The mean proportion of lamellar bone to woven bone in the control group (1.22\u00a0\u00b1\u00a01.48) was significantly greater than the test group (0.38\u00a0\u00b1\u00a00.29) (P<\/jats:italic>\u00a0<\u00a00.05).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>ABBM<\/jats:styled-content>\u2010C exhibited very similar histomorphometric parameters to the composite graft of ABBM<\/jats:styled-content>\u00a0+\u00a0AB<\/jats:styled-content>. The ABBM<\/jats:styled-content>\u00a0+\u00a0AB<\/jats:styled-content> group was more mature as indicated by the significantly greater proportion of lamellar bone when compared to the ABBM<\/jats:styled-content>\u2010C. Improved % OI<\/jats:styled-content> was seen in the zone proximal to the resident bony floor in the ABBM<\/jats:styled-content>\u00a0+\u00a0AB<\/jats:styled-content> group. Based on histological assessment, ABBM<\/jats:styled-content>\u2010C is a suitable bone substitute for the purposes of maxillary sinus augmentation. Its clinical utility may be indicated in cases of sinus membrane perforation and insufficient autogenous bone in the local area.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12694","type":"journal-article","created":{"date-parts":[[2015,9,16]],"date-time":"2015-09-16T05:35:18Z","timestamp":1442381718000},"page":"850-858","source":"Crossref","is-referenced-by-count":39,"title":["A histomorphometric assessment of collagen\u2010stabilized anorganic bovine bone mineral in maxillary sinus augmentation \u2013 a prospective clinical trial"],"prefix":"10.1111","volume":"27","author":[{"given":"Jamil","family":"Alayan","sequence":"first","affiliation":[{"name":"School of Dentistry and Oral Health Centre for Medicine and Oral Health Griffith University Southport Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cedryck","family":"Vaquette","sequence":"additional","affiliation":[{"name":"Institute of Health and Biomedical Innovation Queensland University of Technology Kelvin Grove Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camile","family":"Farah","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research University of Queensland Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saso","family":"Ivanovski","sequence":"additional","affiliation":[{"name":"School of Dentistry and Oral Health Centre for Medicine and Oral Health Griffith University Southport Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12652"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2012.01.020"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01854.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00656.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.7.911"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090686"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01612.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1997.080206.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01733.x"},{"key":"e_1_2_6_11_1","first-page":"25","article-title":"Early loading of implants in the atrophic posterior maxilla: lateral sinus lift with autogenous bone and bio\u2010oss versus crestal mini sinus lift and 8\u2010mm hydroxyapatite\u2010coated implants. A randomised controlled clinical trial","volume":"2","author":"Cannizzaro G.","year":"2009","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_6_12_1","first-page":"237","article-title":"Bone augmentation procedures in implant dentistry","volume":"24","author":"Chiapasco M.","year":"2009","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2003.tb00197.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01565.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2003.tb00198.x"},{"key":"e_1_2_6_16_1","first-page":"86","article-title":"Effect of the macroporosity for osseous substitution of calcium phosphate ceramics","volume":"11","author":"Daculsi G.","year":"1990","journal-title":"Biomaterials"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(84)90092-2"},{"key":"e_1_2_6_18_1","first-page":"565","article-title":"Systematic review of survival rates for implants placed in the grafted maxillary sinus","volume":"24","author":"Fabbro M.","year":"2004","journal-title":"The International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1982.tb00172.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.2500\/105065801779954120"},{"key":"e_1_2_6_21_1","first-page":"543","article-title":"Comparison of mineralized cancellous bone allograft (puros) and anorganic bovine bone matrix (bio\u2010oss) for sinus augmentation: histomorphometry at 26 to 32\u00a0weeks after grafting","volume":"26","author":"Froum S.J.","year":"2006","journal-title":"The International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01814.x"},{"key":"e_1_2_6_23_1","first-page":"337","article-title":"Porous hydroxyapatite for grafting the maxillary sinus: a comparative histomorphometric study in sheep","volume":"17","author":"Haas R.","year":"2002","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1998.090206.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2001.012002135.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2001.tb00236.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2005.tb00055.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2008.00690.x"},{"key":"e_1_2_6_29_1","first-page":"635","article-title":"A clinical and histologic evaluation of implant integration in the posterior maxilla after sinus floor augmentation with autogenous bone, bovine hydroxyapatite, or a 20:80 mixture","volume":"17","author":"Hallman M.","year":"2002","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.00996.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01372.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-005-6988-1"},{"key":"e_1_2_6_33_1","first-page":"55","article-title":"Tissue reaction and material characteristics of four bone substitutes","volume":"11","author":"Jensen S.S.","year":"1996","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02438.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02245.x"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.dmfr.4600601"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2008.07.021"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820100212"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2010.0035"},{"key":"e_1_2_6_40_1","first-page":"873","article-title":"Treatment of maxillary ridge resorption by sinus augmentation with iliac cancellous bone, anorganic bovine bone, and endosseous implants: a clinical and histologic report","volume":"15","author":"Maiorana C.","year":"2000","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.8.911"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01776.x"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.30196"},{"key":"e_1_2_6_44_1","first-page":"593","article-title":"The \u201cloma linda pouch\u201d: a technique for repairing the perforated sinus membrane","volume":"23","author":"Proussaefs P.","year":"2003","journal-title":"The International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_45_1","first-page":"413","article-title":"Repair of the perforated sinus membrane with a resorbable collagen membrane: a human study","volume":"19","author":"Proussaefs P.","year":"2004","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100112630"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2012.09.007"},{"key":"e_1_2_6_48_1","first-page":"201","article-title":"Bio\u2010oss\u2013a resorbable bone substitute?","volume":"8","author":"Schlegel A.K.","year":"1998","journal-title":"Journal of Long\u2010Term Effects of Medical Implants"},{"key":"e_1_2_6_49_1","first-page":"53","article-title":"Histologic findings in sinus augmentation with autogenous bone chips versus a bovine bone substitute","volume":"18","author":"Schlegel A.K.","year":"2003","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02431.x"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12396"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1053\/joms.2001.20494"},{"key":"e_1_2_6_53_1","first-page":"556","article-title":"Maxillary sinus grafting with anorganic bovine bone: a clinical report of long\u2010term results","volume":"18","author":"Valentini P.","year":"2003","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_6_54_1","first-page":"245","article-title":"Sinus grafting with porous bone mineral (bio\u2010oss) for implant placement: a 5\u2010year study on 15 patients","volume":"20","author":"Valentini P.","year":"2000","journal-title":"The International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01877.x"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(00)70090-4"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2005.04.026"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2000.011003217.x"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fclr.12694","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.12694","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:59:02Z","timestamp":1696334342000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.12694"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,16]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1111\/clr.12694"],"URL":"https:\/\/doi.org\/10.1111\/clr.12694","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,16]]}}}