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Recorded data were statistically analyzed evaluating percentage of new bone volume, residual biomaterial, and connective\/soft tissues in the biopsies. A meta\u2010analysis of comparative studies was also performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After article selection process, 84 articles were included in the quantitative synthesis and 16 of them in the meta\u2010analysis of comparative studies. The use of autogenous bone (<jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>) alone led to a significantly higher new bone formation if compared with bovine bone (<jats:styled-content style=\"fixed-case\">BB<\/jats:styled-content>) alone (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04), while no significant difference was found when the latter was compared with a mixture of<jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">BB<\/jats:styled-content>(<jats:italic>P<\/jats:italic>\u00a0=\u00a00.52). Grafts composed of<jats:styled-content style=\"fixed-case\">BB<\/jats:styled-content>showed significantly greater new bone formation as compared to hydroxyapatite (<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) while a mixture of tricalcium phosphate (<jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content>) and<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>achieved better outcomes than<jats:styled-content style=\"fixed-case\">BB<\/jats:styled-content>(<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Based on histomorphometric evaluation,<jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>should still be taken into consideration when the highest possible new bone formation is the primary aim in maxillary sinus surgery. When donor site morbidity is a concern,<jats:styled-content style=\"fixed-case\">BB<\/jats:styled-content>and a mixture of<jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>could be considered as predictable, showing promising results. More comparative histologic studies are needed to confirm such results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12702","type":"journal-article","created":{"date-parts":[[2015,10,10]],"date-time":"2015-10-10T11:32:29Z","timestamp":1444476749000},"page":"1106-1122","source":"Crossref","is-referenced-by-count":114,"title":["Histomorphometric outcomes after lateral sinus floor elevation procedure: a systematic review of the literature and meta\u2010analysis"],"prefix":"10.1111","volume":"27","author":[{"given":"Stefano","family":"Corbella","sequence":"first","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano Milan Italy"},{"name":"IRCCS Istituto Ortopedico Galeazzi Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"Taschieri","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano Milan 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