{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T14:47:59Z","timestamp":1780930079679,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,3,22]],"date-time":"2016-03-22T00:00:00Z","timestamp":1458604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Camlog Foundation","award":["CF41208"],"award-info":[{"award-number":["CF41208"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of the study was to evaluate the feasibility of a standardized Quantitative Sensory Testing (<jats:styled-content style=\"fixed-case\">QST<\/jats:styled-content>) protocol extra\u2010 and intraoral in patients to detect and quantify sensory disturbances of the inferior alveolar nerve due to the proximity of implantation procedures to the inferior alveolar nerve canal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Patients who had obtained an implant placement were examined by implementing a comprehensive <jats:styled-content style=\"fixed-case\">QST<\/jats:styled-content> protocol for extra\u2010 and intraoral use. The study included 33 patients after implant placement in the lower jaw and one patient suffering from an inferior alveolar nerve injury. Patients were tested bilaterally (chin and mucosal lower lip).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Comparing the implanted vs. the control side, <jats:styled-content style=\"fixed-case\">QST<\/jats:styled-content> parameters revealed no significant neurophysiological changes in all parameters. Evaluating the development of sensory disturbances in dependency of the proximity of the implant to the inferior alveolar nerve canal, mechanical <jats:styled-content style=\"fixed-case\">QST<\/jats:styled-content> parameters showed no significant correlation. The mean distance of the inserted implant to the inferior nerve canal was 2.65\u00a0\u00b1\u00a01.75\u00a0mm. In the case of one patient suffering from impairment of the nerve function due to implant placement, we found abnormal sensory responses to touch coexisting with numbness and temperature algesia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Monitoring of trigeminal nerve fiber functions by <jats:styled-content style=\"fixed-case\">QST<\/jats:styled-content> intra\u2010 and extraoral is feasible to evaluate oral sensory pattern after implantation procedures. Sensory disturbances of the inferior alveolar nerve were shown to be avoided by keeping an average safety zone of 2.65\u00a0mm between implant and nerve.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12837","type":"journal-article","created":{"date-parts":[[2016,3,22]],"date-time":"2016-03-22T12:12:22Z","timestamp":1458648742000},"page":"576-581","source":"Crossref","is-referenced-by-count":18,"title":["Neurophysiological changes associated with implant placement"],"prefix":"10.1111","volume":"28","author":[{"given":"Amely","family":"Hartmann","sequence":"first","affiliation":[{"name":"Private Practice Dr. Seiler und Kollegen Filderstadt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Welte\u2010Jzyk","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery University Medical Centre of the Johannes Gutenberg University of Mainz Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Seiler","sequence":"additional","affiliation":[{"name":"Private Practice Dr. Seiler und Kollegen Filderstadt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Daubl\u00e4nder","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery University Medical Centre of the Johannes Gutenberg University of Mainz Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-09-00059"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2014.08.004"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12245"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(99)90720-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2011.01883.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-014-1222-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.23.4.510"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.060197"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2005.06.028"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.5037\/jomr.2011.2101"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02314.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2009.258"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2002.0050"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.03.023"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200003000-00013"},{"key":"e_1_2_6_17_1","first-page":"7","article-title":"Chronic intraoral pain\u2013assessment of diagnostic methods and prognosis","volume":"220","author":"Pigg M.","year":"2011","journal-title":"Swedish Dental Journal. 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