{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T20:25:09Z","timestamp":1789763109901,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,5,19]],"date-time":"2016-05-19T00:00:00Z","timestamp":1463616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Oral Implants Res"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the clinical outcomes of simultaneous guided bone regeneration using native (<jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>) and cross\u2010linked (<jats:styled-content style=\"fixed-case\">VN<\/jats:styled-content>) collagen membranes at 8\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A total of <jats:italic>n<\/jats:italic>\u00a0=\u00a019 patients (19 implants) were available for the analysis. Each subject had received a simultaneous grafting of dehiscence\u2010type defects using a natural bone mineral (<jats:styled-content style=\"fixed-case\">NBM<\/jats:styled-content>) and a random allocation to either <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">VN<\/jats:styled-content> membranes (submerged healing of 4\u00a0months). Clinical parameters (e.g., bleeding on probing \u2013 <jats:styled-content style=\"fixed-case\">BOP<\/jats:styled-content>, probing pocket depth \u2013 <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>, mucosal recession \u2013 <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>, clinical attachment level \u2013 <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content>) were recorded at 8\u00a0years after prosthesis installation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 8\u00a0years, <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">VN<\/jats:styled-content> groups revealed comparable median <jats:styled-content style=\"fixed-case\">BOP<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> PD<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> MR<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> values at both vestibular and oral aspects. From 4 to 8\u00a0years (<jats:italic>n<\/jats:italic>\u00a0=\u00a014 patients), median <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> at the vestibular aspect improved in both groups; however, these changes were significantly higher at <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>\u2010treated sites (<jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>: 0.7\u00a0mm vs. <jats:styled-content style=\"fixed-case\">VN<\/jats:styled-content>: 0.5\u00a0mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The clinical long\u2010term outcomes at 8\u00a0years were comparable in both <jats:styled-content style=\"fixed-case\">VN<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/clr.12881","type":"journal-article","created":{"date-parts":[[2016,5,19]],"date-time":"2016-05-19T18:32:33Z","timestamp":1463682753000},"page":"779-784","source":"Crossref","is-referenced-by-count":17,"title":["Long\u2010term outcomes of simultaneous guided bone regeneration using native and cross\u2010linked collagen membranes after 8\u00a0years"],"prefix":"10.1111","volume":"28","author":[{"given":"Frank","family":"Schwarz","sequence":"first","affiliation":[{"name":"Department of Oral Surgery Universit\u00e4tsklinikum D\u00fcsseldorf D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Schmucker","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery Universit\u00e4tsklinikum D\u00fcsseldorf D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery Universit\u00e4tsklinikum D\u00fcsseldorf D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,19]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"87","article-title":"Use of a new cross\u2010linked collagen membrane for the treatment of peri\u2010implant dehiscence defects: a randomised controlled double\u2010blinded clinical trial","volume":"4","author":"Annen B.M.","year":"2011","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01689.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12039"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.2.215"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01622.x"},{"key":"e_1_2_7_7_1","first-page":"218","article-title":"Bone augmentation procedures in localized defects in the alveolar ridge: clinical results with different bone grafts and bone\u2010substitute materials","volume":"24","author":"Jensen S.S.","year":"2009","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12296"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02522.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01283.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1967.38.6.610"},{"key":"e_1_2_7_12_1","first-page":"435","article-title":"A randomized, controlled clinical evaluation of a synthetic gel membrane for guided bone regeneration around dental implants: clinical and radiologic 1\u2010 and 3\u2010year results","volume":"27","author":"Ramel C.F.","year":"2012","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01108.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12220"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01225.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01486.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02214.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01443.x"},{"key":"e_1_2_7_19_1","first-page":"355","article-title":"Long\u2010term results of implants treated with guided bone regeneration: a 5\u2010year prospective study","volume":"16","author":"Zitzmann N.U.","year":"2001","journal-title":"International Journal of Oral and Maxillofacial Implants"}],"container-title":["Clinical Oral Implants Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fclr.12881","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fclr.12881","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/clr.12881","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T18:24:25Z","timestamp":1694975065000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/clr.12881"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,19]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1111\/clr.12881"],"URL":"https:\/\/doi.org\/10.1111\/clr.12881","archive":["Portico"],"relation":{},"ISSN":["0905-7161","1600-0501"],"issn-type":[{"value":"0905-7161","type":"print"},{"value":"1600-0501","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,19]]}}}